A second-order test in the assessment of vitamin D status, especially in patients with renal disease. Useful for investigation of some patients with clinical evidence of vitamin D deficiency (eg, vitamin D-dependent rickets due to hereditary deficiency of renal 1-alpha hydroxylase or end-organ resistance to 1,25-dihydroxyvitamin D), and differential diagnosis of hypercalcemia.
Serum
SST (1)
Original Collection Vial(s)
1 ML (0.5 ML Minimum)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to separate serum from red cells. Submit unopened collection tube, refrigerate until picked-up.
Useful in the diagnostic workup of patients with congenital adrenal hyperplasia. Useful as part of metyrapone testing in the workup of suspected secondary or tertiary adrenal insufficiency, or as part of metyrapone testing in the differential diagnostic workup of Cushing syndrome.
Serum
SST (1)
Original Collection Vial(s)
1 ML (0.5 ML Minimum)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to separate serum from red cells. Submit unopened collection tube, refrigerate until picked-up.
Morning Specimen Preferred (8AM)
REFRIGERATE (7 Days)
9 Days
Quantitative High Performance Liquid Chromatography/Tandem Mass Spectrometry
Assesses adrenocortical function and reflects cortisol secretions.
Urine
24 Hour Urine Jug (1)
24 Hour Urine Jug
20 ML (10 ML Minimum)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful for monitoring breakdown of adrenal hormones. Aides in the diagnosis of tumors in the ovaries or adrenal cortex.
Urine
24 Hour Urine Jug (1)
24 Hour Urine Jug
4 ML (3 ML Minimum)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
1 of the 3 analytes (along with cortisol and androstenedione) that constitutes the best screening test for congenital adrenal hyperplasia (CAH) caused by either 11- or 21-hydroxylase deficiency. Also useful as part of a battery of tests to evaluate females with hirsutism or infertility. Both can result from adult-onset CAH.
Serum
SST (1)
Plastic Transport Vial
1 ML (0.5 ML Minimum)
Plasma
EDTA (1)
Allow SST tube to clot for 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to separate serum from red cells and immediately aliquot serum into a separate transport vial. Submit transport vial only, refrigerate until picked-up.
Useful for diagnosis and management of carbohydrate metabolism disorders including gestational diabetes and neonatal hypoglycemia in pregnant patients.
Serum X3
SST (3)
Original Collection Vial(s)
1 ML (0.5 ML Minimum)
Plasma X3
Gray (3)
Patient should be drawn for a fasting level, then consume 75g Glucola drink within 5 minutes and without vomiting. Start a timer when drink is finished and then draw as close to the one hour mark as possible, each hour up to the two hour mark. Submit all 3 samples, clearly labeled with time of draw. SST: Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s). GRAY: Gently invert collection tube(s) at least 10 times, immediately post-draw. Submit unopened collection tube(s).
Diagnosis and management of diabetes mellitus and other carbohydrate metabolism disorders including gestational diabetes, neonatal hypoglycemia, idiopathic hypoglycemia, and pancreatic islet cell carcinoma.
Serum X2
SST (2)
Original Collection Vial(s)
1 ML (0.5 ML Minimum)
Plasma X2
Gray (2)
SST: Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s). GRAY: Gently invert collection tube(s) at least 10 times, immediately post-draw. Submit unopened collection tube(s).
Useful in the investigation of adrenal insufficiency and as an aid in the detection of those at risk of developing autoimmune adrenal failure in the future.
Serum
SST (1)
Original Collection Vial(s)
1 ML (0.2 ML Minimum)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to separate serum from red cells. Submit unopened collection tube, refrigerate until picked-up.
Useful for biochemical diagnosis and monitoring of intestinal carcinoid syndrome
Urine
24 Hour Urine Jug (1)
24 Hour Urine Jug
5 ML Minimum
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Keep Urine Refrigerated During Collection. If possible, patient should discontinue use of acetaminophen, asprin, antihistamines, and cough and cold medicine for 48 hours prior to collection. Also limit the following to one serving per day for two days prior to collection: fruits, vegetables, nuts, and caffeinated beverages or foods.
REFRIGERATE (56 Days)
5 Days
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Useful for diagnosing risk factors for patients with calcium kidney stones and monitoring results of therapy in patients with calcium stones or renal tubular acidosis
Urine
24 Hour Urine Jug (1)
24 Hour Urine Jug
4 ML Minimum
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful for monitoring patients with monoclonal gammopathies using 24-hour urine specimens.
Urine
24 Hour Urine Jug (1)
24 Hour Urine Jug
26 ML Minimum
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Keep Urine Refrigerated During Collection
REFRIGERATE (14 Days)
4 Days
Turbidimetry, Agarose Del Electrophoresis, Immunofixation
84156, 84166, 86335
Bence Jones Urine, Heavy Chains Urine, Immunoelectrophoresis, Immunofixation Electrophoresis (IFE), Immunofixation, Kappa Chains Urine, Lambda Chains Urine, Light Chains Urine, Paraprotein, Special Protein Studies
Evaluation of calcium oxalate and calcium phosphate kidney stone risk, and calculation of urinary supersaturations. Evaluation of bone diseases, including osteoporosis and osteomalacia.
Urine (24 Hr)
24 Hour Urine Jug (1)
24 Hour Urine Jug
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
An indicator of fluid balance and acid-base homeostasis.
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Urinary creatinine, in conjunction with serum creatinine, is used to calculate the creatinine clearance, a measure of renal function.
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful in the screening or management of diabetes mellitus
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful for assessing the cause of abnormal serum magnesium concentrations, determining whether nutritional magnesium loads are adequate, calculating urinary calcium oxalate and calcium phosphate supersaturation, and assessing kidney stone risk.
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful for diagnosing risk factors for patients with calcium kidney stones and monitoring results of therapy in patients with calcium stones or renal tubular acidosis
Urine
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful for evaluation of hypophosphatemic or hyperphosphatemic states and evaluation of patients with nephrolithiasis.
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful for determining the cause for hyperkalemia or hypokalemia.
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Keep Urine Refrigerated During Collection
REFRIGERATE (14 Days)
Potentiometric, Indirect Ion-Selective Electrode
84133
K (potassium), Electrolytes Urine, K Urine, Lytes Urine
Useful in evaluation of renal disease and screening for monoclonal gammopathy.
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful for assessing acid-base balance, water balance, water intoxication, and dehydration.
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful in assessment of protein intake and/or nitrogen balance.
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful in assessment and management of patients with kidney stones, particularly uric acid stones.
Urine (24 Hr)
24 Hour Urine Jug (1)
None
None
Have patient collect all urine excretions for a 24 hour period, refrigerating the sample jug between collections. Submit 24 hour urine jug, refrigerate until picked-up.
Useful for diagnosis and management of carbohydrate metabolism disorders including gestational diabetes and neonatal hypoglycemia in pregnant patients.
Serum
SST (4)
Original Collection Vial
1 ML (0.5 ML Minimum)
Plasma X4
Gray (4)
Patient should be drawn for a fasting level, then consume 100g Glucola drink within 5 minutes and without vomiting. Start a timer when drink is finished and then draw as close to the one hour mark as possible, each hour up to the three hour mark. Submit all 4 samples, clearly labeled with time of draw. SST: Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s). GRAY: Gently invert collection tube(s) at least 10 times, immediately post-draw. Submit unopened collection tube(s).
Useful for diagnosis and management of carbohydrate metabolism disorders including gestational diabetes and neonatal hypoglycemia in pregnant patients.
Serum X5
SST (5)
Original Collection Vial
1 ML (0.5 ML Minimum)
Plasma X5
Gray (5)
Patient should be drawn for a fasting level, then consume 100g Glucola drink within 5 minutes and without vomiting. Start a timer when drink is finished and then draw as close to the one hour mark as possible, each hour up to the four hour mark. Submit all 5 samples, clearly labeled with time of draw. SST: Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s). GRAY: Gently invert collection tube(s) at least 10 times, immediately post-draw. Submit unopened collection tube(s).
Useful for diagnosis and management of carbohydrate metabolism disorders including gestational diabetes and neonatal hypoglycemia in pregnant patients.
Serum X6
SST (6)
1 ML (0.5 ML Minimum)
Plasma X6
Gray (6)
Patient should be drawn for a fasting level, then consume 100g Glucola drink within 5 minutes and without vomiting. Start a timer when drink is finished and then draw as close to the one hour mark as possible, each hour up to the five hour mark. Submit all 6 samples, clearly labeled with time of draw. SST: Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s). GRAY: Gently invert collection tube(s) at least 10 times, immediately post-draw. Submit unopened collection tube(s).
Useful for biochemical diagnosis and monitoring of intestinal carcinoid syndrome
Urine
Sterile Urine Cup
Sterile Urine Cup
10 ML (5 ML Minimum)
None
None
Must be sent and received at Unipath on the same day. If not, a preservative must be added. Please contact the lab for further instruction if shipping next day or beyond.
Dietary Restrictions: Avoid foods high in indoles (avocado, banana, tomato, plum, walnut, pineapple, eggplant) and Tobacco, Tea, and Coffee for 3 days prior to collection.
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Must be drawn in a plain red collection tube. Serum from a separator tube (SST) will be rejected.
Useful for the diagnosis and management of carbohydrate metabolism disorders (specifically gestational diabetes) in pregnant patients.
Serum
SST (1)
Plasma
Gray (1)
Exactly one hour prior to draw, patient should consume 50g Glucola drink within 5 minutes and without vomiting. Start a timer when drink is finished and draw as close to the one hour mark as possible. SST: Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s). GRAY: Gently invert collection tube(s) at least 10 times, immediately post-draw. Submit unopened collection tube(s).
REFRIGERATE (7 Days)
Hexokinase/G-6-PDH
82950
GDS, GTT, Gestational Diabetes, One Hour Glucose, 1 Hour GLucose Tollerence, ADA Glucose
Useful for detection and quantification of antibodies directed against adalimumab in serum and trough level quantitation for evaluation of patients with loss of response to adalimumab.
Serum
SST (1)
Original Collection Vial
0.5 ML (0.35 ML Minimum)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to separate serum from red cells. Submit unopened collection tube.
Useful for determining the cause of hypercortisolism and hypocortisolism.
Plasma
EDTA (1)
Plastic Transport Vial
1.0 ML (0.5 ML Minimum)
None
None
Gently invert collection tube(s) at least 10 times, immediately post-draw. Centrifuge unopened collection tube for 15 minutes to separate plasma from red cells. Aliquot plasma into a plastic transport vial and close tightly with a lavendar stopper. Freeze immediately after aliquot and submit frozen plasma.
Dietary Restrictions: Avoid Biotin (B7) for 12 HR Prior. Specimen is a CRITICAL FROZEN, must be aliquotted and frozen as soon as possible.
Useful for aiding in the evaluation of nutritional status, liver function, or causes of edema.
Serum
SST (1)
Plastic Transport Vial
1 ML (0.5 ML Minimum)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to separate serum from red cells. If specimen not received at the lab within 2 hours, aliquot serum into a plastic transport vial and close tightly with a yellow stopper.
Useful in the investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter syndrome)
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), regrigerated.
Useful in the diagnosis and treatment of liver, bone, intestinal, and parathyroid diseases. Also useful for determining the tissue source of increased alkaline phosphatase (ALP) activity in serum, and differentiating between liver and bone sources of elevated ALP.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), regrigerated.
Useful for diagnosis and monitoring of liver disease associated with hepatic necrosis.
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Common food allergy profile. Panel includes: Almond, Cashew, Cob, Cow's Milk, Egg White, Hazelnut, Peanut, Salmon, Scallops, Sesame Seed, Shrimp, Soy Bean, Tuna, Walnut, Wheat, IgE total antibody. Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), refrigerated until picked up.
Seafood allergy profile. Panel includes: Codfish, Crab, Shrimp, Tuna, Lobster. Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), refrigerated until picked up.
Stinging insect allergy profile. Panel includes: Honeybee Venom, Yellow Jacket Venom, Wasp Venom, Yellow Faced Hornet Venom, White Faced Hornet Venom. Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), refrigerated until picked up.
Western region respiratory allergy profile. Panel includes: IgE total antibody, House Dust Mites DP, House Dust Mites DF, Cat Epithelium, Dog Dander, Bermuda Grass, Timothy Grass, Cockroach, Penicillium, Cladosporium, Aspergillus Fumigatus, Alternaria Tenius, Box Elder/Maple, Grey Alder, Mountain Cedar, Oak, Elm, Olive Tree, Cottonwood, Mulberry, Short Ragweed, Mugwort, Russian Thistle, Rough Pigweed, Red Sorrel. Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), refrigerated until picked up.
REFRIGERATE (14 Days)
4 Days
Fluorescence Enzyme Immunoassay (FEIA)
86003 x25
Allergen, Allergy Testing, Tree Allergy, Grass Allergy, Southwest Allergen
Norhteastern region respiratory allergy profile. Panel includes: IgE total antibody, House Dust Mites DP, House Dust Mites DF, Cat Epithelium, Dog Dander, Bermuda Grass, Timothy Grass, Cockroach, Penicillium, Cladosporium, Aspergillus Fumigatus, Alternaria Tenius, Box Elder/Maple, Silver Birch, Mountain Cedar, Oak, Elm, Walnut Tree, Eastern Sycamore, Cottonwood, White Ash, Mulberry, Short Ragweed, Red Sorrel. Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), refrigerated until picked up.
REFRIGERATE (14 Days)
4 Days
Fluorescence Enzyme Immunoassay (FEIA)
86003 x24
Allergen, Allergy Testing, Tree Allergy, Grass Allergy, Northeast Allergen
Useful for workup of individuals with suspected disorders such as familial chronic obstructive lung disease, and diagnosis of alpha-1-antitrypsin deficiency
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), refrigerated until picked up.
Useful for the follow-up management of patients undergoing cancer therapy, especially for testicular and ovarian tumors and for hepatocellular carcinoma. Often used in conjunction with human chorionic gonadotropin.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), refrigerated until picked up.
Useful in the diagnosis and monitoring of liver disease associated with hepatic necrosis.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for the evaluation of patients with possible inborn errors of metabolism using plasma specimens, and may aid in the evaluation of endochrine disorders, liver diseases, muscle diseases, neoplastic diseases, neurological disorders, nutritional disturbances, renal failure, and burns.
Plasma
Green (1)
None
None
Allow Sodium or Lithium Heparin tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Immediately aliquot plasma into a plastic transport vial and freeze.
Fasting is recommended. Must separate cells from plasma within 2 hours and freeze. CRITICAL FROZEN. REQUIRED INFORMATION: age, sex, diet, drug therapy (eg TPN therapy), family history. SEND DEDICATED SPECIMEN.
FREEZE (30 Days)
8 Days
Quantitative Liquid Chromatography/Tandem Mass Spectrometry
Useful for monitoring amiodarone therapy (especially when amiodarone is coadministered with other drugs that may interact) and the evaluation of possible amiodarone toxicity. Also used to assess patient compliance.
Serum
Red (1)
Plasma
EDTA (1)
Submit unopened collection tube, refrigerated until picked up.
Useful for monitoring serum concentration during therapy and evaluating potential toxicity. Also may be used to evaluate patient compliance.
Serum
Red (1)
Plasma
EDTA (1)
Submit unopened collection tube, refrigerated until picked up. If not picked up within 7 hours, allow collection tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Aliquot serum into plastic transport vial and refrigerate.
Useful to help diagnose severe liver disease and certain genetic urea cycle disorders, to help investigate the cause of changes in behavior and consciousness, and to support the diagnosis of hepatic encephalopathy and Reye’s syndrome
Plasma
EDTA (1)
None
None
Immediately post-draw, gently invert collection tube at least 10 times. Submit unopened collection tube.
Useful for the diagnosis and managament of pancreatitis and the evaluation of pancreatic function.
Serum
SST (1)
None
Red (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s), refrigerated until picked up. MUST centrifuge and seperate within 2 hours of collection.
Centrifuge and separate within 2 hours of collection.
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to separate serum from red cells. Submit unopened collection tube, refrigerate if not picked up same-day.
REFRIGERATE (7 Days)
4 Days
Indirect Fluorescent Antibody
86039, 86225, 86235 x6
ANA1, ANA2, Antinuclear Antibody, Hep-2, FANA (Fluorescent Antinuclear Antibodies), LE (Lupus Erythematosus) Prep, ANA Screen
Useful in the screening for and diagnosis of certain autoimmune diseases.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to separate serum from red cells. Submit unopened collection tube, refrigerate if not picked up same-day.
REFRIGERATE (7 Days)
4 Days
Indirect Fluorescent Antibody
86039
ANA1, ANA2, Antinuclear Antibody, Hep-2, FANA (Fluorescent Antinuclear Antibodies), LE (Lupus Erythematosus) Prep, ANA Screen
Useful for diagnosis and differential diagnosis of hyperandrogenism (in conjunction with measurements of other sex-steroids) and diagnosis of congenital adrenal hyperplasia (CAH) in conjunction with measurement of other androgenic precursors. Also used to monitor CAH treatment, in conjunction with testosterone, DHEA-S, OHPG, and DHEA, and in the diagnosis of premature adrenarche in conjunction with gonadotropins and other adrenal and gonadal sex-steroids and their precursors.
Serum
Red (1)
Plasma
EDTA (1)
Invert collection tube 10x post-draw and submit unopened collection tube for testing.
Useful for the evaluation of patients with suspected sarcoidosis
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to seperate serum from red cells. Submit unopened collection tube, refrigerated if not picked up same-day.
Please indicate if the patient is on ACE inhibitors.
Useful for monitoring antibody levels during pregnancy to help assess the risk of hemolytic disease of the newborn. This test is not useful for monitoring the efficacy of Rh-immune globulin administration.
Whole Blood, Serum
Pink (1) and Red (1)
None
None
Specimen must arrive at Unipath on the same day of the draw. Draw into both a plain red and a pink EDTA collection tube. Invert collection tubes 10x post-draw and submit unopened collection tube for testing.
Both Plasma and Serum are required along with RBCs. Specimen must arrive at Unipath on the same day as the draw.
Useful in the assessment of menopausal status including premature ovarian failure, and in assessing ovarian status including ovarian reserve and ovarian responsiveness. Useful as part of an evaluation for infertility and assisted reproduction protocols such as in vitro fertilization, and in assessing ovarian function in patients with polycystic ovarian syndrome. Also useful for evaluation of infants with ambiguous genitalia and other intersex conditions, evaluating testicular function in infants and children, and monitoring patients with antimullerian hormone-secreting ovarian granulosa cell tumors.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to seperate serum from red cells. Submit unopened collection tube, refrigerated if not picked up same-day.
Useful in the demonstration of acute or recent streptococcal infection.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube for 15 minutes to seperate serum from red cells. Submit unopened collection tube, refrigerated if not picked up same-day.
Useful for the diagnosis of antithrombin deficiency (acquired or congenital) and for monitoring treatment of antithrombin deficiency disorders including infusion of antithrombin therapeutic concentrate.
Plasma
Lt. Blue (1)
None
None
As soon as possible post-draw, spin collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial and freeze.
CRITICAL FROZEN
FREEZE (1 Month) CRITICAL
4 Days
Chromogenic
85300
Antithrombin Activity, AT3 Activity/Functional, AT III Activity/Functional, Anti-Thrombin III, TEST
As soon as possible post-draw, spin collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial and freeze.
CRITICAL FROZEN
FREEZE (1 Month) CRITICAL
4 Days
Latex Immunoassay
85301
Immunologic Antithrombin III, AT III Antigen/Immunologic, AT3 Antigen/Immunologic
Useful as an adjunct in the diagnosis of autoimmune thyroid diseases such as: Hashimoto disease, postpartum thyroiditis, neonatal hypothyroidism, and Graves disease. Also useful in the identification of potentially unreliable serum thyroglobulin measurements by immunoassay and in the follow-up of patients with differentiated follicular-cell derived thyroid carcinomas.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in the diagnosis of metabolic disorders and for assessing risk or coronary artery (CAD) and atherosclerotic cardiovascular diseases. Aides in the diagnosis of Tangier disease.
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
REFRIGERATE (7 Days)
4 Days
Nephelometry
82172
Apo A, Apo A-1, Apo A1, ApoA, ApoA-1, ApoA1, Apolipoprotein A-I, Apolipoprotein A1, Apolipoprotein AI
Useful for the assessment of residual risk in patients at target non high-density lipoprotein-cholesterol (HDL-C) or low-density lipoprotein-cholesterol (LDL-C). Used for follow-up studies in individuals with non-HDL-C (or LDL-C) values inconsistent with risk factors or clinical presentation, for definitive studies of cardiac risk factors in individuals with significant family histories of coronary artery disease or other increased risk factors, and for confirmation of suspected abetalipoproteinemia or hypobetalipoproteinemia.
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
REFRIGERATE (7 Days)
4 Days
Nephelometry
82172
Apo B, APO-B, APOB, APOB-100, Apolipoprotein B1, Apolipoprotein B-100
Useful in monitoring heparin therapy, screening for certain coagulation factor deficiencies, and for the detection of coagulation inhibitors such as lupus anticoagulants, specific factor inhibitors, and nonspecific inhibitors.
Plasma
Lt. Blue (1)
None
None
Spin collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial and freeze.
Draw tube MUST be filled to line. Pour off plasma and freeze within 4 hours of draw.
Useful for diagnosing and monitoring liver disease, particularly diseases resulting in a destruction of hepatocytes.
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for determining the current status of kidney function, electrolyte and acid/base balance, and level of blood glucose.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in evaluation of patients with suspected antiphospholipid syndrome by identification of beta-2 glycoprotein 1 (beta-2 GP1) IgG and IgM antibodies.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
FREEZE (14 Days)
5 Days
Enzyme immunoassay
86146 x2
Beta-2 GP1 Ab IgG, Beta-2 GP1 Ab IgM, B2GMG (Beta-2 Glycoprotein 1)
Useful in the prognosis assessment of multiple myeloma and the evaluation of renal tubular disorders.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for measuring tauro- and glycol-conjugated and unconjugated bile acid constituents in serum to aide in the diagnosis of intrahepatic cholestasis of pregnancy (ICP).
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for measuring tauro- and glycol-conjugated and unconjugated bile acid constituents in serum, for monitoring patients receiving bile acid therapy (such as cholic acid, deoxycholic acid, or ursodeoxycholic acid), for aiding in the evaluation of liver function, and for the evaluation of liver function changes before the formation of more advanced clinical signs of illness such as icterus. Also useful for determining hepatic dysfunction as a result of chemical and environmental injury, for indicating hepatic histological improvement in chronic hepatitis C patients responding to interferon treatment, and for indicating intrahepatic cholestasis of pregnancy (ICP).
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Detection of ethanol in blood to document prior consumption or administration of ethanol; quantification of the concentration of ethanol in blood correlates directly with degree of intoxication.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Draw two specimens from two seperate sites. Be sure to fill bottles to line on outside of label. Submit samples in original collection containers. Do not freeze or refrigerate.
FDA-approved cancer-associated antigen (CA 27.29) for serial testing in women with prior stage II or III breast cancer who are clinically free of disease. Useful for predicting early recurrence of disease in women with treated carcinoma of the breast, and to indicate that additional tests or procedures should be performed to confirm recurrence of breast cancer
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. As soon as possible, centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells, aliquot into a plastic transport vial, and freeze.
Pour Off Within 2 HR. CRITICAL FROZEN.
FREEZE (90 Days) CRITICAL
4 Days
Chemiluminometric Immunoassay
86300-90
Biomira Truquant BR, Breast Cancer Tumor Markers, Breast Carcinoma, Cancer Antigen 27.29 (CA 27.29), MAM 6, Milk Mucin, CA2729
Useful as a screening test for evaluation of kidney function
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Aids in the diagnosis and follow-up of medullary thyroid carcinoma and in the evaluation of multiple endocrine neoplasia type II and familial medullary thyroid carcinoma.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. As soon as possible, centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells, aliquot into a plastic transport vial, and freeze.
Useful in the diagnosis and monitoring of a wide range of disorders including diseases of bone, kidney, parathyroid gland, or gastrointestinal tract Calcium levels may also reflect abnormal vitamin D or protein levels.
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for assessing calcium states during liver transplantation surgery, cardiopulmonary bypass, or any procedure requiring rapid transfusion of whole blood in neonates and critically ill patients. Also useful as a second-order test in the evaluation of patients with abnormal calcium values.
Useful for evaluation of patients suspected of having a gastrointestinal inflammatory process and distinguishing inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS) when used in conjunction with other diagnostic modalities, including endoscopy, histology, and imaging.
Useful for evaluating patients' response to ovarian cancer therapy and Predicting recurrent ovarian cancer. Not useful for cancer detection screening in the normal population.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
REFRIGERATE (72 Hours)
4 Days
Chemiluminescence
86304
CA125, Carbohydrate Antigen 125, OV Monitor, Ovarian Cancer-Related Antibodies, Cancer Ag 125, CA 125
Aides in managing breast cancer patients when used in conjunction with clinical information and other diagnostic procedures. Serial testing can assist in early detection of disease recurrence in previously treated stage II and III breast cancer patients. Also useful for monitoring response to therapy in metastatic breast cancer patients
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Dietary Restrictions: Avoid Biotin (B7) for 12 HR Prior
REFRIGERATE (7 Days)
4 Days
Electrochemiluminescence Immunoassay (ECLIA)
86300-90
CA 15-3, CA153, MUC-1, Mucin-Like Carcinoma-Associated Antigen
Useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms. May also be used to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms. Testing also may be useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to allergens, drugs, or chemical allergens.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for monitoring carbamazepine (free) therapy in uremic patients, and for monitoring unbound or free carbamazepine levels in patients where the total carbamazepine result is within the therapeutic range but the patient is experiencing side effects.
Potentially useful adjunct for diagnosis and monitoring of pancreatic cancer. May be useful for differentiating patients with cholangiocarcinoma and primary sclerosing cholangitis (PSC) from those with PSC alone.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
FREEZE (14 Days)
4 Days
Chemiluminescence
86301-90
CA 19-9, Cancer Antigen 19-9, Carbohydrate Antigen 19-9, GI Cancer Antigen
Useful for monitoring colorectal cancer and selected other cancers such as medullary thyroid carcinoma. May be useful in assessing the effectiveness of chemotherapy or radiation treatment, but is not useful in screening the general population for undetected cancers.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Testing for cardiolipin (phospholipid) antibodies is indicated in the following clinical situations: Unexplained arterial or venous thrombosis, a history of pregnancy morbidity defined as 1 or more unexplained deaths of a morphologically normal fetus beyond the 10th week of gestation, 1 or more premature births before 34 weeks of gestation caused by severe preeclampsia or placental insufficiency, or 3 or more unexplained, consecutive spontaneous abortions before the 10th week of gestation with no identifiable maternal hormonal or anatomic, or maternal or paternal chromosomal causes. Useful in the presence of an unexplained cutaneous circulatory disturbance (eg, livido reticularis or pyoderma gangrenosum), in the presence of an unexplained cutaneous circulatory disturbance (eg, livido reticularis or pyoderma gangrenosum). Also useful in the presence of a systemic rheumatic disease (especially lupus erythematosus), an unexplained thrombocytopenia or hemolytic anemia, and possible nonbacterial thrombotic endocarditis.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for the evaluation of patients with suspected antiphospholipid syndrome by identification of phospholipid antibodies.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in the evaluation of patients with a clinical suspicion of a wide range of conditions including organic acidemias, fatty acid oxidation disorders, and primary carnitine deficiency.
Plasma
Green (1) Sodium OR Lithium Heparin
Plastic Transport Vial
0.5 mL
Serum
Red (1)
Centrifuge and aliquot plasma into plastic transport vial within 2 hours of collection and freeze promptly. Submit frozen plasma in plastic transport vial.
Useful as an auxiliary test to fractionated plasma and urine metanephrine measurements in the diagnosis of pheochromocytoma and paraganglioma. Also used as an auxiliary test to urine vanillylmandelic acid and homovanillic acid determination in the diagnosis and follow-up of patients with neuroblastoma and related tumors.
Urine
24 Hour Urine Jug (1)
None
None
Avoid drugs that hinder metabolism of epinephrine or dopamine for at least 1 week prior to draw, if possible.
Useful in the diagnosis of pheochromocytoma and paraganglioma, as an auxiliary test to fractionated plasma and urine metanephrine measurements (plasma metanephrine is the preferred test for this diagnosis), in the diagnosis and follow-up of patients with neuroblastoma and related tumors, as an auxiliary test to urine vanillylmandelic acid and homovanillic acid measurements, and in the evaluation of patients with autonomic dysfunction or failure or autonomic neuropathy.
Plasma
Green (2) Sodium Heparin ICED CRITICAL FROZEN
None
None
Draw in chilled vacutainer and place immediately into ice bath. Send 4.0 mL plasma CRITICAL FROZEN in two vials.
FREEZE (30 Days)
8 Days
High Performance Liquid Chromatography with Electrochemical Detection
Useful as a screening tool to confirm a hematologic disorder, detection of an unsuspected hematologic disorder, and/or to monitor effects of radiation or chemotherapy.
Useful as a screening tool to confirm a hematologic disorder, detection of an unsuspected hematologic disorder, and/or to monitor effects of radiation or chemotherapy.
Useful for evaluating patients suspected of having rheumatoid arthritis (RA) and for differentiating RA from other connective tissue diseases that may present with arthritis.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in serial monitoring of CD4 T cell count in HIV-positive patients, for follow-up and diagnostic evaluation of primary cellular immunodeficiencies (including severe combined immunodeficiency), for T-cell immune monitoring following immunosuppressive therapy for transplantation, autoimmunity, and other immunological conditions where such treatment is utilized. Also used in the assessment of T-cell immune reconstitution post hematopoietic cell transplantation, and in early screening of gross quantitative anomalies in T cells in infection or malignancies.
Whole Blood
EDTA (2)
None
None
Send 4.0 mL whole blood within 24 HR of draw. Serial monitoring draws should be performed at same time of day.
RT (72 Hours)
3 Days
Flow Cytometry, Single Platform
86359, 86360
CD4 Count, Immune Competence, Immune Status, Quantitative CD4, T Cell(s), T-Cell(s), T Lymphocyte Surface Markers, T-Cell Surface Markers, T-Helper, AIDS (Acquired Immune Deficiency Syndrome)
Useful for determining ratio of CD4 to CD8 cells to evaluate immune strength and predict infection in HIV, leukemia, aplastic anemia, MS, myasthenia graves, and Hodgkin diseases.
Whole Blood
EDTA (2)
None
None
Send 4.0 mL whole blood. Collect MON-THURS only, do not send Friday.
RT (72 Hours)
4 Days
Flow Cytometry
86360
CD4 Count, CD8 Count, Helper Suppressor Ratio, Immune Competence, Immune Status, Immunodeficiency Panel, Quantitative CD4 and CD8, T Cell(s), T-Cell(s), T Lymphocyte Surface Markers, T-Cell Surface Markers, T-Helper/T-Suppressor, T4/T8 Helper Suppressor Ratio, AIDS (Acquired Immune Deficiency Syndrome)
Useful for evaluating patients suspected of having celiac disease, including patients with compatible symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disease, positivity for DQ2 and/or DQ8).
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in evaluating patients with clinical signs and symptoms compatible with systemic sclerosis including skin involvement, Raynaud phenomenon, and arthralgias. Useful in aiding in the diagnosis of calcinosis, Raynaud phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasis (CREST) syndrome.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for investigation of patients with possible Wilson disease.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for evaluation of water, electrolyte, and acid-base status
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful to determine if you have been exposed to and/or poisoned by certain organophosphate chemicals found in pesticides, to monitor cholinesterase levels if you work with pesticides, or to identify individuals with inherited pseudocholinesterase deficiency before they are given anesthesia with the muscle relaxant succinylcholine. Can also help determine the cause of prolonged apnea after surgical anesthesia.
Useful for the follow-up or surveillance of patients with known or treated carcinoid tumors, as an adjunct in the diagnosis of carcinoid tumors, as an adjunct in the diagnosis of other neuroendocrine tumors (including pheochromocytomas, medullary thyroid carcinomas, functioning and nonfunctioning islet cell and gastrointestinal amine precursor uptake and decarboxylation tumors, and pituitary adenomas), and as a possible adjunct in outcome prediction and follow-up in advanced prostate cancer
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in diagnosis of heart attack, finding the cause of chest pain, or finding out how much heart or muscle tissue has been damaged. Can also determine whether you carry the gene for muscular dystrophy including dermatomyositis, polymyositis, malignant hyperthermia, and other conditions that may cause muscle breakdown.
Serum
SST (1)
None
None
Pour Off Within 4HR
REFRIGERATE (7 Days)
6 Days
Electrophoresis/Spectrophotometry
82550, 82552
CK (Creatine Kinase), CK Isoenzyme Electrophoresis, CK Macro, CK-BB, CK-MM, CPK (Creatine Phosphokinase), Isoenzyme of Creatine Kinase, Macro CK, Macro Creatine Kinase, Mitochondrial Creatine Kinase, CPK Isoenzyme Electrophoresis
Useful for the diagnosis and treatment of acid-base imbalance in respiratory and metabolic systems
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for diagnosing deficiencies, particularly hemophilia B (Christmas disease), assessing the impact of liver disease on hemostasis, and investigation of a prolonged activated partial thromboplastin time.
Plasma
Lt. Blue (1)
None
None
Centrifuge collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial. Centrifuge transport vial again and pipette all but the bottom 0.25 mL of plasma into a seperate transport vial and freeze. Must be dedicated specimen.
PT must not be on Coumadin or heparin therapy. Spin TWICE and pour off within 4 HR of collection. CRITICAL FROZEN.
FREEZE (14 Days)
4 Days
Optical Clot-Based
85250
Factor IX Activity Assay, Hemophilia B, Factor IX, Factor 9
Useful for diagnosing congenital deficiencies of coagulation factor V, investigation of prolonged prothrombin time or activated partial thromboplastin time, and evaluating acquired deficiencies associated with liver disease, factor V inhibitors, myeloproliferative disorders, and intravascular coagulation and fibrinolysis.
Plasma
Lt. Blue (1)
None
None
Centrifuge collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial. Centrifuge transport vial again and pipette all but the bottom 0.25 mL of plasma into a seperate transport vial and freeze. Must be dedicated specimen.
PT must not be on Coumadin or heparin therapy. Spin TWICE and pour off within 4 HR of collection. CRITICAL FROZEN.
Useful for diagnosing congenital deficiency of coagulation factor VII and evaluating acquired deficiencies associated with liver disease, oral anticoagulant therapy, and vitamin K deficiency. Also useful for determining degree of anticoagulation with warfarin to correlate with level of protein C, and for investigation of a prolonged prothrombin time.
Plasma
Lt. Blue (1)
None
None
Centrifuge collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial. Centrifuge transport vial again and pipette all but the bottom 0.25 mL of plasma into a seperate transport vial and freeze. Must be dedicated specimen.
PT must not be on Coumadin or heparin therapy. Spin TWICE and pour off within 4 HR of collection. CRITICAL FROZEN.
FREEZE (14 Days)
4 Days
Optical Clot-Based
85230
Coagulation Factor VII Assay, FACTOR VII ACTIVITY, Prothrombin, Factor VII, Factor 7
Useful in the diagnosing hemophilia A, the diagnosis of von Willebrand disease when measured with the von Willebrand factor (VWF) antigen and VWF activity, and the diagnosing acquired deficiency states. Also useful in the investigation of prolonged activated partial thromboplastin time, and in monitoring infusions of factor VIII replacement during interventional procedures and prophylactic infusions.
Plasma
Lt. Blue (1)
None
None
Centrifuge collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial. Centrifuge transport vial again and pipette all but the bottom 0.25 mL of plasma into a seperate transport vial and freeze. Must be dedicated specimen.
PT must not be on Coumadin or heparin therapy. Spin TWICE and pour off within 4 HR of collection. CRITICAL FROZEN.
FREEZE (14 Days)
4 Days
Optical Clot-Based
85240
Coagulation Factor VIII Activity Assay, Factor VIII Activity Assay, Hemophilia A, Factor VIII, Factor 8
Useful for diagnosing deficiency of coagulation factor X (congenital or acquired), in evaluating hemostatic function in liver disease, and in the investigation of prolonged prothrombin time or activated partial thromboplastin time.
Plasma
Lt. Blue (1)
None
None
Centrifuge collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial. Centrifuge transport vial again and pipette all but the bottom 0.25 mL of plasma into a seperate transport vial and freeze. Must be dedicated specimen.
Spin TWICE and pour off within 4 HR of collection. CRITICAL FROZEN.
Useful in diagnosing deficiency of coagulation factor XI, and investigation of prolonged activated partial thromboplastin time
Plasma
Lt. Blue (1)
None
None
Centrifuge collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial. Centrifuge transport vial again and pipette all but the bottom 0.25 mL of plasma into a seperate transport vial and freeze. Must be dedicated specimen.
PT must not be on Coumadin or heparin therapy. Spin TWICE and pour off within 4 HR of collection. CRITICAL FROZEN.
FREEZE (14 Days)
4 Days
Optical Clot-Based
85270
Factor XI Activity Assay. F11, Factor XI, Factor 11
Useful for diagnosing deficiency of coagulation factor XII, and for determining cause of prolonged activated partial thromboplastin time.
Plasma
Lt. Blue (1)
None
None
Centrifuge collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial. Centrifuge transport vial again and pipette all but the bottom 0.25 mL of plasma into a seperate transport vial and freeze. Must be dedicated specimen.
PT must not be on Coumadin or heparin therapy. Spin TWICE and pour off within 4 HR of collection. CRITICAL FROZEN.
FREEZE (14 Days)
4 Days
Optical Clot-Based
85280
Coagulation Factor XII Activity Assay, Factor XII, Factor 12
Useful for detecting cobalt toxicity and monitoring metallic prosthetic implant wear.
Serum
Dark Blue Trace Element (1)
Plasma
Dark Blue EDTA (1)
Invert tube 10 times immediately post-draw. Within 2 hours of draw, centrifuge collection tube for 15 minutes to seperate plasma from red cells. Without using a pipette, gently pour-off all possible plasma into a metal-free transport vial. Leave ambient at room temperature.
Discontinue vitamin, mineral, herbal supplements, and an non-essential medications prior to draw. USE METAL FREE POUR OFF TUBE.
RT
9 Days
Quantitative Inductively Coupled Plasma - Mass Spectrometry
Useful when used to evaluate or monitor the rate of bone formation and resorption. It is a useful tool to detect the presence of Paget disease and monitor the progress of osteoporosis. Typically ordered when there could be the presence of a metabolic bone disease.
Useful when assessing disease activity in systemic lupus erythematosus (SLE) and/or investigating an undetectable total complement (CH50) level.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
REFRIGERATE (8 Days)
4 Days
Nephelometry
86160
3rd Component of Complement, C3 COMP, C3, Third Component of Complement
Useful when investigating an undetectable total complement (CH50), confirming hereditary angioedema (with low C1 inhibitor), and for assessing disease activity in systemic lupus erythematosus, proliferative glomerulonephritis, rheumatoid arthritis, and autoimmune hemolytic anemia.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
REFRIGERATE (8 Days)
4 Days
Nephelometry
86160
4th Component of Complement, C4, Fourth Component of Complement, Hereditary Angioedema Panel
Broad screening tool to evaluate organ function and check for conditions such as diabetes, liver disease, and kidney disease. Used to monitor known conditions, such as hypertension, and to monitor people taking specific medications for any kidney or liver-related side effects.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Broad screening tool to evaluate organ function and check for conditions such as diabetes, liver disease, and kidney disease. Used to monitor known conditions, such as hypertension, and to monitor people taking specific medications for any kidney or liver-related side effects.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Fasting Preferred (12 HR)
REFRIGERATE (7 Days)
Various (See individual test methodology)
80053
CMPC, CMP with calcs, Chemistry Panel with Calculations, Chemistry Screen with Calculations
Useful when discriminating between primary and secondary adrenal insufficiency and in the differential diagnosis of Cushing syndrome.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
The preferred screening test for Cushing Syndrome. Useful in the diagnosis of pseudo-hyperaldosteronism due to excessive licorice consumption. Assists in the diagnosis of acquired or inherited abnormalities of 11-beta-hydroxy steroid dehydrogenase. This test has limited usefulness in the evalution of adrenal insufficiency.
Urine
Sterile Container (1)
None
None
FREEZE (28 Days)
6 Days
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Useful in a diagnostic workup of hypoglycemia through diagnosis of factitious hypoglycemia due to surreptitious administration of insulin, in the evaluation of possible insulinoma, and as a surrogate measurement for the absence or presence of physiological suppressibility of endogenous insulin secretion during diagnostic insulin-induced hypoglycemia (C-peptide suppression test). Also useful for assessing insulin secretory reserve in diabetic patients who either have insulin autoantibodies or who are receiving insulin therapy.
Creatine kinase is utilized in the diagnosis and monitoring of myocardial infarction and myopathies such as the progressive Duchenne muscular dystrophy.
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in the risk assessment for developing myocardial infarction in patients presenting with acute coronary syndromes, and in the risk assessment for developing cardiovascular disease or ischemic events in individuals who do not manifest the disease at present.
Serum
SST (1)
NONE
NONE
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
REFRIGERATE (7 Days)
Turbidimetric/Immunoturbidimetric
86141
C Reactive Protein Cardiac, C Reactive Protein High Sensitivity, C-Reactive Protein Cardio, C-Reactive Protein Sensitive, CRP Cardiac, CRP Highly Sensitive, CRP Ultra-Sensitive, Sensitive C-Reactive Protein, Ultra-Sensitive C-Reactive Protein, CRPC, HSCRP
Useful for estimation of glomerular filtration rate.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for detecting systemic inflammatory processes, for detecting infection and assessing response to antibiotic treatment of bacterial infections, and for differentiating between active and inactive disease forms with concurrent infection.
Serum
SST (1)
NONE
NONE
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for evaluating cryoglobulins in patients with vasculitis, glomerulonephritis, and lymphoproliferative diseases, and in evaluating patients with macroglobulinemia or myeloma in whom symptoms occur with cold exposure.
Serum
Red (1) Clot in Warm Water
None
None
Allow sample to clot in warm water before serum is spun and separated from cells.
Useful for monitoring whole blood cyclosporine concentration during therapy (particularly in individuals coadministered CYP3A4 substrates, inhibitors, or inducers), for adjusting dose to optimize immunosuppression while minimizing toxicity, and fort evaluating patient compliance.
Whole Blood
EDTA (1)
None
None
Draw immediately before scheduled dose. DO NOT centrifuge. Send in original collection tube.
REFRIGERATE (14 Days)
2 Days
High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS)
Aiding in the diagnosis of acute or past infection with cytomegalovirus (CMV) and determination of prior exposure to CMV.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Aiding in the diagnosis of acute infection with cytomegalovirus (CMV).
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for the detection and quantification of cytomegalovirus (CMV) viremia, and for monitoring CMV disease progression and response to antiviral therapy.
Plasma
EDTA (1)
None
None
DEDICATED SPECIMEN REQUIRED. Centrifuge and separate within 24 hours.
REFRIGERATE (5 Days)
4 Days
PCR
87497
Cytomegalovirus detection by PCR, CMV by PCR, CMV DNA Quant, CMV Viral Load
Determining whether a patient (especially transplant recipients, organ, and blood donors) has had a recent infection or previous exposure to cytomegalovirus.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for evaluating patients suspected of having autoimmune vasculitis (both Wegener granulomatosis [WG] and microscopic polyangiitis). May be useful for monitoring treatment response in patients with WG (systemic or organ-limited disease); increasing titer suggests relapse of disease, while a decreasing titer suggests successful treatment.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for diagnosis of intravascular coagulation and fibrinolysis (disseminated intravascular coagulation) especially when combined with clinical information and other laboratory test data. Also useful for excluding the diagnosis of acute pulmonary embolism or deep vein thrombosis.
Plasma
Lt. Blue (1)
None
None
Draw tube MUST be filled to line. Pour off plasma and freeze within 4 hours of draw.
Useful for the diagnosis and differential diagnosis of hyperandrogenism (in conjunction with measurements of other sex steroids) or as an adjunct in the diagnosis of congenital adrenal hyperplasia (CAH). DHEA/DHEA-S measurements play a secondary role to the measurements of cortisol/cortisone, 17 alpha-hydroxyprogesterone, and androstenedione.
Useful for diagnosis and differential diagnosis of hyperandrogenism (in conjunction with measurements of other steroids), and as an adjunct in the diagnosis of congenital adrenal hyperplasia. Useful in the diagnosis and differential diagnosis of premature adrenarche.
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in the assessment of an antibody response to tetanus and diphtheria toxoid vaccines, which should be performed at least 3 weeks after immunization. Aids in the evaluation of immunodeficiency.
Useful for evaluation of jaundice and liver functions.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for demonstrating in vivo coating of RBCs with IgG or the complement component C3d in the following settings: autoimmune hemolytic anemia, hemolytic transfusion reactions, or drug-induced hemolytic anemia.
Useful for the diagnosis and monitoring of autoimmune diseases, specifically Lupus.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
REFRIGERATE (72 Hours)
4 Days
Enzyme Immunoassay
86225
Anti-DNA, Anti-ds (Anti-Double Stranded) DNA, ANTI-dsDNA ANTIBODY, Antibody to ds-DNA, Antibody to Native DNA (n-DNA), Connective Tissue Disease Activity Assessment, Connective Tissue Disease Autoantibody Panel, DNA Double Stranded (ds-DNA) Antibody, Double Stranded DNA, ds-DNA Antibody, Autoantibodies to Double Stranded (ds)DNA, Native Anti-DNA, Native DNA, SLE (Systemic Lupus Erythematosus)
Useful as a rapid screening for preliminary qualitative results of multiple drugs and drug metabolites including: Amphetamines, Barbiturates, Benzodiazepines, Cannabinoids, Cocaine Metabolites, Phencyclidine, Morphine, Methamphetamine, Methadone, Oxycodone,
Urine
Sterile Container (1)
None
None
RT (72 Hours)
Lateral Flow Chromatographic Immunoassay
80305, G0480
Drug Test, Drug Abuse, Drug Screen, Urine Toxicology, Drugs of Abuse
Although urine is the specimen of choice for drug screening, a serum drug screen can be performed when a urine specimen is unavailable (autopsy, dialysis patient).
Serum
Red (2)
Plasma
EDTA (1)
REFRIGERATE (14 Days)
4 Days
Enzyme-Multiplied Immunoassay Technique
High Performance Liquid Chromatography/Liquid Chromatography/Tandem Mass Spectrometry
80307, 80377, G0481
Drug Test, Drug Abuse, Drug Screen, Serum Toxicology, Drugs of Abuse
A third-order test in the diagnosis of infectious mononucleosis, especially in situations when initial testing results (heterophile antibody test) are negative and follow-up testing (viral capsid antigen: VCA IgG, VCA IgM, and Epstein-Barr nuclear antigen) yields inconclusive results aiding in the diagnosis of type 2 or type 3 nasopharyngeal carcinoma
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
REFRIGERATE (14 Days)
4 Days
Multiplex Flow Immunoassay
86663
E. B. Virus (Early Antigen), EA, Early Antigen, EBV EARLY AG, Epstein Barr Virus Early Ag Ab, Epstein-Barr Virus (EBV) Early Antigen
Useful in diagnosing infectious mononucleosis when a mononucleosis screening procedure is negative and infectious mononucleosis or a complication of Epstein-Barr virus infection is suspected.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
REFRIGERATE (48 Hours)
4 Days
Chemiluminescent Immunoassay
86663, 86664, 86665 x2
Anti EBV Serology, E. B. (Epstein-Barr) Virus, EBNA (Epstein-Barr Nuclear Antigen), EBV Battery, EBV Panel, EBV, Epstein-Barr Virus AB, Epstein-Barr Virus Battery, Epstein-Barr Virus Panel, VCA (Viral Capsid Antigen) IgG and IgM, Viral Capsid Antigen (VCA) Titer, Infectious Mononucleosis, EBV Ab
Useful for the evaluation of electrolyte status and acid-base balance.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for the diagnosis of dermatitis herpetiformis and celiac disease, and for monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
This culture is used by long-term care facilities to monitor the environment. Laboratory should be contacted prior to environmental sampling by other customers. This test is not intended to be used for monitoring the sterility of duodenoscopes, endoscopes, or pharmacy products and solutions.
Useful when diagnosing infectious mononucleosis when a mononucleosis screening procedure is negative and infectious mononucleosis or a complication of Epstein-Barr virus infection is suspected.
Whole Blood
EDTA (1)
CSF
CSF
REFRIGERATE (8 Days)
7 Days
Real-Time PCR
87799
EBV, EBV Detection by PCR, EBV Detection by Real-Time PCR, Epstein-Barr Virus Detection by PCR, Epstein-Barr Virus Detection by Polymerase Chain Reaction (PCR), Epstein-Barr Virus Detection by Real-Time PCR, Infectious Mononucleosis, LightCycler EBV, Epstein-Barr PCR
An aid in distinguishing between primary and secondary polycythemia, differentiating between appropriate secondary polycythemia (eg, high-altitude living, pulmonary disease, tobacco use) and inappropriate secondary polycythemia (eg, tumors). Also useful when identifying candidates for erythropoietin (EPO) replacement therapy (eg, chronic renal failure), and when evaluating patients undergoing EPO replacement therapy who demonstrate an inadequate hematopoietic response.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Collection at same time of day recommended (7:30am-12:00pm).
Useful for applications that require moderately sensitive measurement of estradiol including evaluation of hypogonadism and oligo-amenorrhea in females, assessing ovarian status (including follicle development) for assisted reproduction protocols, in conjunction with luteinizing hormone measurements and monitoring of estrogen replacement therapy, evaluation of feminization (including gynecomastia) in males, diagnosis of estrogen-producing neoplasms as part of a diagnosis of precocious and delayed puberty, diagnosis of suspected disorders of sex steroid metabolism (aromatase deficiency and 17 alpha-hydroxylase deficiency). Also useful as an adjunct to clinical assessment, imaging studies, and mineral density of fracture risk assessment to postmenopausal women and older men and for monitoring low-dose female hormone replacement therapy and antiestogen therapy.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
A marker of fetal demise, also useful in assessment of preterm labor risk.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for evaluation of patients for ovarian estrogen producing tumors in the premenarcheal and postmenopausal female, and for evaluating estrogen levels in males and diagnosis of endocrine disorders. Analyzing estrogen can also aid in establishing time of ovulation and optimal time for conception.
Serum
SST (2)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for simultaneous high-sensitivity determination of serum estrone and estradiol levels. Useful in applications that require moderately sensitive measurement of estradiol, and in situations requiring either higher sensitivity estradiol measurement, estrone measurement, or both.
Serum
Red (1)
None
None
Pour off within 2 HR of collection.
REFRIGERATE (28 Days)
5 Days
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS
82670, 82679
E1 (Estrone), Estradiol, Estrogens, Estrone, Total Estrogens
Useful as part of the diagnosis and workup of precocious and delayed puberty in females and (to a lesser degree) males, as part of the diagnosis and workup of suspected disorders of sex steroid metabolism (eg, aromatase deficiency and 17 alpha-hydroxylase deficiency). Also useful for monitoring antiestrogen therapy (eg, aromatase inhibitor therapy) and low-dose female hormone replacement therapy in postmenopausal women, and as an adjunct to clinical assessment, imaging studies, and bone mineral density measurement in the fracture risk assessment of postmenopausal women and (to a lesser degree) older men.
Useful for diagnosing a congenital deficiency of coagulation factor II, for evaluating acquired deficiencies associated with liver disease or vitamin K deficiency, oral anticoagulant therapy, and antibody-induced deficiencies (eg, in association with lupus-like anticoagulant). Also useful for determining warfarin treatment stabilization in patients with nonspecific inhibitors (ie, lupus anticoagulant), determining degree of anticoagulation with warfarin to correlate with level of protein S, and the investigation of prolonged prothrombin time or activated partial thromboplastin time.
Useful for patients with clinically suspected thrombophilia and either activated protein C (APC)-resistance proven or suspected by a low or borderline APC-resistance ratio, or a family history of factor V Leiden.
Whole Blood
EDTA (1)
None
None
RT (5 Days)
6 Days
The genotype is determined by Invader-based detection for the normal and mutant (R506q) alleles in genomic DNA isolated from blood.
81241
Activated protein C (APC) resistance mutation, APC resistance mutation, Factor V Leiden mutation
Useful for diagnosing fat malabsorption due to pancreatic or intestinal disorders and monitoring effectiveness of enzyme supplementation in certain malabsorption disorders.
Stool
Sterile Container (1)
None
None
Avoid castor oil, fat substitutes such as olestra, suppositories, or barium prior to collection.
Useful for diagnosing fat malabsorption due to pancreatic or intestinal disorders and monitoring effectiveness of enzyme supplementation in certain malabsorption disorders.
Stool
Sterile Container (1)
None
None
Eat a diet consisting of 50-150 g of fat per day for three days prior to study. Use only screw-capped containers and do not overfill- if collection exceeds 500mL/500g, use another container.
Useful for diagnosing fat malabsorption due to pancreatic or intestinal disorders and monitoring effectiveness of enzyme supplementation in certain malabsorption disorders.
Stool
Sterile Container (1)
None
None
Eat a diet consisting of 50-150 g of fat per day for three days prior to study. Use only screw-capped containers and do not overfill- if collection exceeds 500mL/500g, use another container.
Useful for diagnosing fat malabsorption due to pancreatic or intestinal disorders and monitoring effectiveness of enzyme supplementation in certain malabsorption disorders.
Stool
Sterile Container (1)
None
None
Eat a diet consisting of 50-150 g of fat per day for three days prior to study. Use only screw-capped containers and do not overfill- if collection exceeds 500mL/500g, use another container.
Useful for diagnosing iron deficiency and iron-overload conditions.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for detecting increased or decreased fibrinogen (factor 1) concentration of acquired or congenital origin and monitoring severity and treatment of disseminated intravascular coagulation and fibrinolysis.
Plasma
Lt. Blue (1)
None
None
Draw tube MUST be filled to line. Pour off plasma and freeze within 4 hours of draw.
Useful in the investigation of suspected folate deficiency
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
A thyroid function test providing further confirmation of hyperthyroidism, supplementing the T4, TSH, and total T3 assays.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Free thyroxine is measured together with thyroid-stimulating hormone when thyroid function disorders are suspected.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Measures the amount of unattached, or "free," testosterone and useful for diagnosing hormonal disorders in men and women.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Used as an adjunct in the evaluation of menstrual irregularities and evaluation of suspected hypogonadism, and for predicting ovulation, evaluating infertility, and diagnosing pituitary disorders.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Used as an adjunct in the evaluation of menstrual irregularities and evaluation of suspected hypogonadism, and for predicting ovulation, evaluating infertility, and diagnosing pituitary disorders.
Serum
SST (1)
Plasma
EDTA (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in the diagnosis and treatment of the etiologic agents of fungemia, and for a select patient population that presents with signs and symptoms of sepsis, especially fever of unknown origin.
Whole Blood
Green (1)
None
None
Send in original container.
RT (7 Days)
34 Days
Conventional broth culture technique with identification by macroscopic and microscopic morphology, nucleic acid hybridization probes, D2 rDNA gene sequencing, real-time polymerase chain reaction (rtPCR), or MALDI-TOF mass spectrometry. Dimorphic pathogen identification is confirmed using molecular methods (ie, nucleic acid hybridization probes, D2 rDNA gene sequencing, rtPCR or MALDI-TOF mass spectrometry).
Useful when diagnosing fungal infections from specimens other than blood, skin, hair, nails, and vagina (separate tests are available for these specimen sites).
Varies
VARIES (1)
None
None
Specimen source required, must arrive within 24HR of collection.
Useful when monitoring therapy for vulvovaginitis, when managing chronic recurring disease, and for determining the etiology of infectious vaginitis when other tests have been uninformative.
Swab
Swab (1)
None
None
Specimen source required, must arrive within 24HR of collection.
Useful in the evaluation of individuals with Coombs-negative nonspherocytic hemolytic anemia, and as a rapid test to assess glucose-6-phosphate dehydrogenase (G6PD) enzyme capacity prior to Rasburicase therapy.
Useful for assessing susceptibility to autoimmune (type 1, insulin-dependent) diabetes mellitus and related endocrine disorders (eg, thyroiditis and pernicious anemia), for distinguishing between patients with type 1 and type 2 diabetes, for confirming susceptibility to organ-specific neurological disorders (eg, myasthenia gravis, Lambert-Eaton syndrome), and for confirming a diagnosis of stiff-man syndrome, autoimmune encephalitis, cerebellitis, brain stem encephalitis, or myelitis.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful in the investigation of patients with achlorhydria or pernicious anemia, in the investigation of patients suspected of having Zollinger-Ellison syndrome, and in the diagnosis of gastrinoma.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for the diagnosis and management of carbohydrate metabolism disorders (specifically gestational diabetes) in pregnant patients.
Serum
SST (1)
Plasma
Gray (1)
Exactly one hour prior to draw, patient should consume 50g Glucola drink within 5 minutes and without vomiting. Start a timer when drink is finished and draw as close to the one hour mark as possible. SST: Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s). GRAY: Gently invert collection tube(s) at least 10 times, immediately post-draw. Submit unopened collection tube(s).
Useful for diagnosing and monitoring hepatobiliary disease, it is currently the most sensitive enzymatic indicator of liver disease. Also useful for ascertaining whether observed levels of alkaline phosphatase are due to skeletal disease or reflect the presence of hepatobiliary disease. Can be used as a screening tool for occult alcoholism.
Serum
SST (1)
Plasma
Green (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful when evaluating patients suspected of having celiac disease, including patients with symptoms compatible with celiac disease, patients with atypical symptoms, and individuals at increased risk of celiac disease. Also useful for evaluating the response to treatment with a gluten-free diet.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for evaluating patients with rapid onset renal failure or pulmonary hemorrhage, and as an aid in the diagnosis of Goodpasture syndrome.
Serum
SST (1)
None
None
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Useful for diagnosing and managing diabetes mellitus and other carbohydrate metabolism disorders including gestational diabetes, neonatal hypoglycemia, idiopathic hypoglycemia, and pancreatic islet cell carcinoma.
Serum
SST (1)
Plasma
Gray (1)
Allow SST tube to clot for at least 15 minutes post-draw. Centrifuge unopened collection tube(s) for 15 minutes to separate serum from red cells. Submit unopened collection tube(s).
Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease and to define the allergens responsible for eliciting signs and symptoms. Also useful to identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of allergic reactions to drugs or chemical allergens.
Used to provide preliminary information concerning the type of organisms present directly from clinical specimens or from growth on culture plates. Used to identify the presence of microorganisms in normally sterile body fluids (cerebrospinal fluid, synovial fluid, pleural fluid, peritoneal fluid). Also used to screen sputum specimens to establish acceptability for bacterial culture. Useful in guiding initial antimicrobial therapy.
Useful in the diagnosis of acromegaly and assessment of treatment efficacy (in conjunction with glucose suppression test), and in the diagnosis of human growth hormone deficiency (in conjunction with growth hormone stimulation test)
Diagnostic testing for Helicobacter pylori infection in pediatric patients suspected to have active H pylori infection and/or monitoring response to therapy.
Breath Kit
Breath Kit (1)
None
None
Fast 1HR prior and see instructions for kit collection (PTs 3-17 years)
Useful for the detection and quantification of hepatitis B virus (HBV) DNA in serum of patients with chronic HBV infection (ie, hepatitis B surface antigen-positive) and for monitoring disease progression in chronic HBV infection and response to anti-HBV therapy.
Plasma
EDTA (2)
None
None
Pour off plasma within 6 hours of collection. Dedicated 3.0mL plasma sample required.
REFRIGERATE (3 Days)
6 Days
PCR
87517
HBV DNA, HBV PCR, HBV Quantification, HBV DNA Quantitation, HBV Viral load, Hepatitis B Viral Load, Hepatitis B Quantitation, Hep B
Useful in monitoring patients with treated epithelial ovarian cancer for recurrence or progression. This test should not be used as a screening test for ovarian cancer.
Useful for establishing or confirming the clinical diagnosis of hereditary hemochromatosis (HH) in adults, for testing of individuals with increased transferrin-iron saturation in serum and serum ferritin. With appropriate genetic counseling, can be used as predictive testing of individuals who have a family history of HH. HFE genetic testing is NOT recommended for population screening.
Whole Blood
EDTA (1)
None
Green (1) Sodium Heparin -or- Yellow ACD (1)
RT
13 Days
Fluorescent Restriction Fragment Length Polymorphism - Polymerase Chain Reaction (PCR)
Useful when distinguishing large deletional hereditary persistence of fetal hemoglobin from other conditions with increased percentage of fetal hemoglobin, and when determining the distribution of Hb F within red blood cells.
Whole Blood
EDTA (1)
None
None
REFRIGERATE (7 Days)
6 Days
Flow Cytometry
88184
Acid Elution Test for Fetal Hgb, Fetal Hemoglobin, Hemoglobin F Red Cell Distribution, Hemoglobin-F Distribution
Useful as a screening tool to confirm a hematologic disorder, detect an unsuspected hematologic disorder, and/or monitor effects of radiation or chemotherapy.
Whole Blood
EDTA (1)
None
None
REFRIGERATE (48 Hours)
Photometry and hemoglobinometry
85027
CBC with Manual Differential, CBC Manual Diff, CBC without differential
Useful for determining hepatitis C virus (HCV) genotype (1 to 5) to guide antiviral therapy in patients with chronic hepatitis C, and for differentiating between HCV subtypes 1a and 1b. Should be performed only on specimens obtained from patients confirmed to have HCV RNA levels in serum of 500 IU/mL or higher.
Plasma
EDTA (2)
Serum
Red (2)
Pour off within 6 HR and freeze. Dedicated specimens required.
Useful for measuring heparin concentration in patients treated with low-molecular-weight heparin preparations, in the presence of prolonged baseline activated partial thromboplastin time (APTT), and when unfractionated heparin dose needed to achieve desired APTT prolongation is higher than expected.
Useful for the diagnosis of recent or past hepatitis B infection and the determination of occult hepatitis B infection in otherwise healthy hepatitis B virus (HBV) carriers with negative test results for hepatitis B surface antigen, anti-hepatitis B surface, anti-hepatitis B core IgM, hepatitis Be antigen, and anti-HBe.
Serum
SST (1)
Plasma
EDTA (1)
REFRIGERATE (5 Days)
4 Days
Chemiluminescence
86704
Hep B Core Ab, HBC, HBCAB, Anti-Hepatitis Bc, Antibody to Hepatitis Bc, Hepatitis B Virus (HBV), Hepatitis Bc
Useful for determining infectivity of hepatitis B virus (HBV) carriers, for monitoring infection status of chronically HBV-infected patients, and for monitoring serologic response of chronically HBV-infected patients who are receiving antiviral therapy.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
REFRIGERATE (6 Days)
Enzyme immunoassay
86705
Hep B Core Ab, HBC, HBCAB, Anti-Hepatitis Bc, Antibody to Hepatitis Bc, Hepatitis B Virus (HBV), Hepatitis Bc
Useful for determining infectivity of hepatitis B virus (HBV) carriers, monitoring infection status of individuals with chronic hepatitis B, monitoring serologic response of chronically HBV-infected patients receiving antiviral therapy, and for determining the level of hepatitis B e-antibody.
Useful for determining infectivity of hepatitis B virus (HBV) carriers, monitoring infection status of individuals with chronic hepatitis B, monitoring serologic response of chronically HBV-infected patients receiving antiviral therapy, and for determining the level of hepatitis B e-antigen.
Useful for the detection and identification of codon substitutions in the hepatitis C virus (HCV) NS5A genomic region that confer resistance to current direct-acting antiviral (DAA) drugs used for treatment of chronic hepatitis C infection due to HCV genotype 1a, 1b, or 3 (any subtype). Also useful in guiding initiation or change of antiviral drug combinations for the treatment of chronic HCV infection.
Useful for the diagnosis of recent or chronic hepatitis C virus infection in symptomatic patients. It is not offered as a screening or confirmatory test for hepatitis C virus (HCV) for blood, human cells, or tissue donors.
Plasma
EDTA (2)
Serum
Red (2)
Pour off within 6 HR and freeze. Dedicated specimens required.
Useful for detection of hepatitis D virus (HDV)-specific total antibodies (combined IgG and IgM) in human serum, for diagnosis of concurrent HDV infection in patients with acute hepatitis B virus (HBV) infection (acute coinfection), for diagnosis of chronic HBV infection (chronic coinfection), or for acute exacerbation of known chronic HBV infection (HDV superinfection).
Serum
SST (1)
Plasma
EDTA (1)
Pour off within 2 HR and freeze.
FREEZE
8 Days
Enzyme Immunoassay
86692 RUO
AHDV, Anti-HDV, Delta hepatitis, HDV, Hepatitis D, Hepatitis D virus antibodies, Hepatitis delta total antibodies
Useful when determining whether a patient has been previously exposed to herpes simplex virus (HSV) types 1 and 2.
Serum
SST (1)
None
None
Allow SST to clot for at least 15 minutes post-draw. As soon as possible, spin collection tube for 15 minutes to seperate plasma from red cells. Using a pipette, aliquot all available plasma into a plastic transport vial and freeze.
Useful for direct detection and differentiation of HSV-1 and HSV-2 DNA in various specimen types from symptomatic patients. It aids in the diagnosis of HSV infection in symptomatic patients.
Varies
VARIES (1)
None
None
Specimen source required (see site link for additional information).
REFRIGERATE (7 Days)
4 Days
Real-Time PCR
87529 x2
HSV PCR, HSV (Herpes Simplex Virus) by PCR (Polymerase Chain Reaction), Herpes Simplex Virus Detection by Real-Time PCR
Used as a marker for methylation status, and to determine the presence of histadelia or histapenia. Utilized as an accurate marker for under methylation or over methylation
Useful in the confirmation and differentiation of HIV-1 and HIV-2 antibodies in plasma specimens that show reactive results with third-(HIV-1/-2 antibody only) and fourth-generation (HIV antigen and antibody) HIV serologic assays. This test is not useful as a screening test for HIV infection in symptomatic or asymptomatic individuals. It is not to be used as a screening or confirmatory test for blood donor specimens.
Plasma
EDTA (1)
Plastic Transport Vial
1 mL (0.8 mL Minimum)
None
None
Gently invert tube at least 10 times post-collection. Centrifuge and seperate plasma from cells within 2 hours of collection. Aliquot plasma into plastic transport vial and freeze.
Centrifuge and seperate plasma within 2 hours of collection.
Useful for determining HIV genotype to guide antiviral therapy and for differentiating between HIV subtypes. Should not be used as a screening test for HIV infection.
Plasma
EDTA (2)
Original Collection Vial(s)
5.0 mL (1.6 mL Minimum)
None
None
Gently invert the tube at least 10 times post-collection. Submit unopened collection tube.
Useful for diagnosis of HIV-1 infection in individuals with acute or early HIV-1 infection, and for diagnosis of HIV-1 infection in infants under 18 months of age born to mothers living with HIV-1.
Plasma
EDTA (2)
None
None
Pour off within 6 HR of collection. Send 3.0 mL plasma frozen. Dedicated specimen required.
Useful when determining whether a patient has been previously exposed to herpes simplex virus (HSV) types 1 and 2, and for distinguishing between infection caused by HSV types 1 and 2, especially in patients with subclinical or unrecognized HSV infection.
Useful in the evaluation of patients with suspected diseases associated with elevations in total immunoglobulin E (IgE) including allergic disease, primary immunodeficiencies, infections, malignancies, or other inflammatory diseases. Also used as a diagnostic evaluation of patients with suspected allergic bronchopulmonary aspergillosis, and the identification of candidates for omalizumab (anti-IgE) therapy
Serum
SST (1)
Plasma
EDTA (1)
REFRIGERATE (7 Days)
4 Days
Fluorescent Enzyme Immunoassay
82785
IgE, Immunoglobulin E, Immune Competence, Total IgE
Detects antibodies floating freely in the blood that could act against certain red blood cells. Used to diagnose potential reactions to a blood transfusion.
Useful for predicting the future development of type 1 diabetes in asymptomatic children, adolescents, and young adults when used in conjunction with family history, HLA-typing, and other autoantibodies, including GD65S/81596 Glutamic Acid Decarboxylase (GAD65) Antibody Assay, and serum and islet cell antigen 2 (IA-2) antibodies. Used for differential diagnosis of type 1 versus type 2 diabetes, for evaluating diabetics with insulin resistance in patients with established diabetes (type 1 or type 2), and for the investigation of hypoglycemia in nondiabetic subjects.
Useful for evaluation of growth disorders, growth hormone deficiency or excess in children and adults, monitoring of recombinant human growth hormone treatment, and follow-up of individuals with acromegaly and gigantism.
Useful for diagnosis of growth disorders, for diagnosing adult growth hormone deficiency, for monitoring of recombinant human growth hormone treatment, and as a possible adjunct to insulin-like growth factor 1 and growth hormone in the diagnosis and follow-up of acromegaly and gigantism.
Useful for the determination of iodine overload using serum specimens, and monitoring iodine levels in individuals taking iodine-containing drugs.
Serum
Dark Blue Trace Element (1)
None
None
Do not use iodine disinfectant during draw. Do not collect if PT has been administered gadolinium or iodine-containing contrast media in past 96 HR. Must use metal free vials and collection tubes. Do not pipette.
Useful to aid in the distinction between the myeloproliferative neoplasm polycythemia vera (PV) and other secondary erythrocytosis. Mutations in JAK2 have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders.
Plasma
EDTA (2)
None
None
REFRIGERATE (5 Days)
13 Days
PCR
81403
JAK2, JAK 2, JAK Mutation, JAK2 Exon 12, Polycythemia Vera, Myeloproliferative Neoplasm (MPN)
Useful when evaluating patients with signs and symptoms compatible with a connective tissue disease, especially those patients with muscle pain and limb weakness, concomitant pulmonary signs and symptoms, Raynaud phenomenon, and arthritis.
Serum
SST (1)
None
None
Do not collect from PTs receiving B12 injection therapy within the last week. CRITICAL FROZEN
FREEZE (14 Days) CRITICAL
4 Days
Enzyme Immunoassay
86235
Antibodies to Jo 1 Antigen, Autoantibodies to Jo 1 Antigen, Histidyl-tRNA Synthetase Antibodies, Polymyositis Antibodies, Jo 1 Antigen, Jo 1 Antibodies
Useful for identifying the presence of urine as a cause for accumulation of fluid in a body compartment and measuring the ultrafiltration capacity of the peritoneal membrane in patients receiving peritoneal dialysis.
Measures qualitative Immunofixation Electrophoresis and quantitative Nephelometry.
Urine
Sterile Container (1)
None
None
REFRIGERATE (21 Days)
10 Days
Nephelometry
83883 x2
Monoclonal Protein Study, Bence Jones Urine, Heavy Chains Urine, Immunoelectrophoresis, Immunofixation, Kappa Chains, Lambda Chains, Light Chains, Paraprotein, Special Protein Studies, Immunofixation Electrophoresis (IFE)
Useful for investigating a variety of diseases involving the heart, liver, muscle, kidney, lung, and blood. Also used to differentiating heart-synthesized lactate dehydrogenase (LD) from liver and other sources, for investigating unexplained causes of LD elevations, and the detection of macro-LD.
Serum
SST (1)
None
None
Pour off into 2 tubes with 1.0 mL serum in each (2.0 mL total).
Useful for monitoring serum concentration of lamotrigine, assessing compliance, and adjusting lamotrigine dose in patients receiving other anticonvulsant drugs which interact pharmacokinetically with lamotrigine.
Useful in the investigation of a variety of diseases involving the heart, liver, muscle, kidney, lung, and blood. Also used to monitor changes in tumor burden after chemotherapy.
Useful for monitoring serum concentration of levetiracetam, particularly in patients with renal disease, assessing compliance, and assessing potential toxicity.
Useful for assessment and management of a patient's risk for atherosclerotic cardiovascular disease, and for identifying residual risk that may be present in some patients on cholesterol targeting treatment.
Serum
Red (1)
None
None
Fasting Required (12 HR). Pour off within 8 HR.
REFRIGERATE (1 Month)
9 Days
Quantitative Nuclear Magnetic Resonance Spectroscopy
Useful for monitoring therapy of patients with bipolar disorders, including recurrent episodes of mania and depression, and for evaluating lithium toxicity.
Serum
SST (1)
None
None
Draw 8-12 hours after last dose (trough specimen). Pour off specimen within 2 HR of collection.
Useful for confirming or excluding the presence of lupus anticoagulant (LAC), distinguishing LAC from specific coagulation factor inhibitors and nonspecific inhibitors, and investigating a prolonged activated thromboplastin time (especially when combined with other coagulation studies). It is not useful for the detection of antiphospholipid antibodies that do not affect coagulation tests, we recommend separate testing for serum phospholipid (cardiolipin) antibodies.
Plasma
Lt. Blue (2)
None
None
PT should not be on warfarin therapy for 2 weeks or heparin therapy for 2 days prior to collection. CRITICAL FROZEN.
FREEZE (1 Month) CRITICAL
4 Days
Clotting
856123, 85598, 85732
APTT Mixing Studies, Coag, Dilute Russell Viper Venom Time (DRVVT), Phospholipid Antibodies, Platelet Neutralization Procedure (PNP Coag Consult)
Useful as an adjunct in the evaluation of menstrual irregularities, evaluation of suspected hypogonadism, predicting ovulation, evaluating infertility, and diagnosing pituitary disorders.
Useful for supporting the diagnosis of Lyme disease in conjunction with serologic testing and for testing synovial fluid or synovium to support the diagnosis of Lyme arthritis.
Varies
VARIES (1)
None
None
Specimen source required.
REFRIGERATE (7 Days)
5 Days
Real-Time PCR/DNA Probe Hybridization
87476, 87798 x2, 87999
Borrelia burgdorferi by PCR, Tick-Borne Diseases, Spirochetes, Lyme Disease, Sensu lato group, Borrelia garinii, Borrelia afzelii, Borrelia mayonii, Borrelia burgdorferi sensu lato genogroup
Spin SST to seperate serum as soon as blood has clotted (approximately 15 minutes) and refrigerate until picked up. Do not draw after amniocentesis. Draw only in pregnancies between 15 weeks 0 days and 22 weeks 6 days.
Uselful for determining acute-phase infection with rubeola (measles) virus using IgM antibody testing, and aids in the identification on nonimmune individuals through IgM antibody testing.
Serum
SST (1)
None
None
Centrifuge and separate from cells within 2 hours.
Useful as a second-order screening test for the presumptive diagnosis of pheochromocytoma in patients with nonepisodic hypertension, and for confirming positive plasma metanephrine results in patients with nonepisodic hypertension.
Urine
Sterile Container (1)
None
None
If possible, discontinue any Tricyclic antidepressant and beta blockers (labetalol and sotalol) at least one week prior to collection.
A first- and second-order screening test for the presumptive diagnosis of catecholamine-secreting pheochromocytomas and paragangliomas. Useful for confirming positive plasma metanephrine results.
Urine
24 Hour Urine Jug (1)
None
None
If possible, discontinue any Tricyclic antidepressant and beta blockers (labetalol and sotalol) at least one week prior to collection.
REFRIGERATE (7 Days)
6 Days
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Stable Isotope Dilution Analysis
Screening test for presumptive diagnosis of catecholamine-secreting pheochromocytomas or paragangliomas.
Plasma
EDTA (1) Chill
None
None
Fasting required (12 HR). Avoid alcohol, coffee, tea, tobacco, and strenuous exercise prior to collection. Draw in a comfortable position. Use pre-chilled collection tubes and place on wet ice until spun. Pour off within 2 hours of collection.
Useful for determining whether methotrexate is being cleared appropriately and verifying that a nontoxic concentration has been attained following therapy.
Serum
Red (2)
Plasma
EDTA (1)
CRITICAL FROZEN, PROTECT FROM LIGHT, PFL (Pour off using Amber Vial)
FREEZE (6 Months) CRITICAL PFL (Pour off using Amber Vial)
Useful for evaluating individuals with signs and symptoms associated with a variety of causes of cobalamin (vitamin B12) deficiency and children with signs and symptoms of methylmalonic acidemia.
Useful for diagnosis of monoclonal gammopathies when used in conjunction with urine monoclonal studies, and for monitoring patients with monoclonal gammopathies. Protein electrophoresis alone is not considered an adequate screen for monoclonal gammopathies.
Serum
SST (1)
None
None
Fasting Preferred (12 HR)
REFRIGERATE (14 Days)
4 Days
Biuret, Agarose Gel Electrophoresis, Immunofixation
84155, 84165, 86334
Monoclonal Protein Study, Immunoelectrophoresis, Immunofixation, Immunotyping, MGUS (Monoclonal Gammopathy of Unknown Significance), Kappa Chains, Lambda Chains, Light Chains, Paraprotein, Special Protein Studies, IFE (Immunofixation Electrophoresis)
Useful for evaluating the cause of elevated homocysteine levels, sometimes to help determine your risk of thrombosis or premature cardiovascular disease (CVD).
Useful for determination of postimmunization immune response of individuals to the mumps vaccine and/or documentation of previous infection with mumps virus in an individual with no previous record of immunization to mumps virus
Useful for the detection and identification of Mycobacterium species, Nocardia species, and other aerobic actinomycetes. Identification is performed using the Hologic/GenProbe AccuProbes for selected Mycobacterium species, matrix assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry, or 500-base pair 16S rRNA gene sequencing. M tuberculosis complex species identification can be done upon request using rapid PCR targeting the regions of difference (RD) genomic areas.
Various
VARIES (1)
None
None
Specimen source required.
REFRIGERATE (7 Days)
43 Days
Automated Detection of Positive Cultures Followed by Organism Identification with Rapid Methods, which may include Nucleic Acid Probes, DNA Sequencing, and Matrix Assisted Laser Desorption/Ionization-Time of Flight (MALDI-TOF) Mass Spectrometry.
87116, 87015, 87118, 87153, 87176, 87150 x2
Acid Fast Bacilli (AFB) Smear, Acid Fast Smear, Acid Fast Bacillus, Culture for TB (Tuberculosis), Mycobacteria, Nocardia, TB Culture
An indirect test for Mycobacterium tuberculosis infection, to be used in conjunction with risk assessment, radiography, and other medical and diagnostic evaluations.
TB Gold Kit
TB Gold Kit (1)
None
None
Tubes must be filled to line. Shake 10 times after collection to mix. Use a waste tube for butterfly collections. DO NOT RERIGERATE OR FREEZE.
INCUBATE
4 Days
Interferon Gamma Release Assay (IGRA) using ESAT-6 and CFP-10 Peptide Antigens
Useful for evaluating patients suspected of having immune-mediated vasculitis, especially microscopic polyangiitis (MPA), when used in conjunction with other autoantibody tests.
Serum
SST (1)
None
None
REFRIGERATE (48 Hours)
4 Days
Enzyme-Linked Immunoassay
83516
ANCA (Antineutrophil Cytoplasmic Antibodies), Anti-Myeloperoxidase Antibodies, Antibodies to Myeloperoxidase, Anticytoplasmic Autoantibodies, Antineutrophil Cytoplasmic Antibodies (ACPA), Autoantibodies to Myeloperoxidase, Autoantibodies to Proteinase 3, Cytoplasmic Neutrophil Antibodies, MPO, Neutrophil Cytoplasmic Antibodies, Wegener's Granulomatosis, Perinuclear Antineutrophil Cytoplasmic Antibody (pANCA)
Useful for confirming the presence of a myopathy associated with any one of the following disorders: hereditary myoglobinuria, phosphorylase deficiency, sporadic myoglobinuria, exertional myoglobinuria in untrained individuals, crush syndrome, myocardial infarction, myoglobinuria of progressive muscle disease, and heat injury. May suggest a myopathic cause for acute renal failure.
Useful for determining Vitamin B3 deficiency and in the diagnosis of pellegra.
Serum
Red (1)
Plasma
EDTA (2)
Must spin and pour-off sample within 2 hours of collection. PLASMA has additional requirements, must PFL and pour-off within 30 minutes. Draw SERUM whenever possible. (Pour off using Amber Vial)
Useful for monitoring effectiveness of antiresorptive therapy in patients treated for osteoporosis or other metabolic bone disorders and as an adjunct in the diagnosis of medical conditions associated with increased bone turnover.
Serum
SST (1)
None
None
CRITICAL FROZEN. For monitoring therapy, baseline samples should be collected just prior to therapy initiation. Samples for comparison, should be collected at approximately the same time of day as the baseline.
FREEZE (2 Months) CRITICAL
11 Days
Enzyme Immunoassay
82523
Collagen Crosslinks, Crosslinked N-telopeptide of Type I Collagen (NTX), NTX, Osteomark, Osteoporosis, N-terminal Telopeptide
Useful as an adjunct in the diagnosis of medical conditions associated with increased bone turnover, and for monitoring effectiveness of antiresorptive therapy in patients treated for osteopenia, osteoporosis, Paget disease, or other metabolic bone disorders.
Urine
Sterile Container (1)
None
None
Do not take biotin (B7) for 24 hours prior to collection. Collect second morning void.
Useful for the detection and quantification of codeine, hydrocodone, oxycodone, morphine, hydromorphone, oxymorphone, noroxycodone, noroxymorphone, norhydrocodone, dihydrocodeine, and naloxone in urine.
Useful for monitoring and assessing effectiveness of antiresorptive therapy in patients treated for osteopenia, osteoporosis, Paget's disease, or other disorders in which osteocalcin levels are elevated. Also useful as an adjunct in the diagnosis of medical conditions associated with increased bone turnover, including Paget's disease, cancer accompanied by bone metastases, primary hyperparathyroidism, and renal osteodystrophy. This test is not useful for the diagnosis of osteoporosis. The diagnosis of osteoporosis should be made on the basis of bone density or clinical history of low-trauma fracture.
Useful for detection and identification of parasitic protozoa and the eggs and larvae of parasitic helminths.
Stool
SAF STL (1) Orange
None
None
Collection should be delayed until 10 days after administration of barium, bismuth, kaolin, magnesia, castor oil, or mineral oil, and 3 weeks prior to completion of antibiotic treatment.
RT (21 Days)
5 Days
Microscopic
87177, 87209
O and P (Ova and Parasites), O&P, Trichrome Stain, Egg Cyst, Parasitic Exam, Protozoa, Amoeba, Ameba, Ova, Helminth, Isopora belli, Cystoisospora, Parasites
Monitoring for appropriate therapeutic concentration of free phenytoin and/or assessing compliance and toxicity. Free phenytoin level is the best indicator of adequate therapy in renal failure.
Potassium should be monitored during treatment of many conditions but especially in diabetic ketoacidosis and any intravenous therapy for fluid replacement. Used in the evaluation of electrolyte balance, cardiac arrythmia, muscular weakness, hepatic encephalopathy, and renal failure.
Used as an ancillary test for congenital adrenal hyperplasia, particularly in situations in which a diagnosis of 21-hydroxylase and 11-hydroxylase deficiency have been ruled out. Useful for confirming a diagnosis of 3-beta-hydroxy dehydrogenase deficiency.
Useful in the diagnosis of bacteremia and septicemia in adults and children (including neonates), the diagnosis of renal involvement in urinary tract infection in children, the diagnosis of bacterial infection in neutropenic patients, the diagnosis, risk stratification, and monitoring of septic shock, the diagnosis of systemic secondary infection post-surgery (and in severe trauma, burns, and multiorgan failure). Also useful in the differential diagnosis of bacterial versus viral meningitis, and community-acquired bacterial versus viral pneumonia. Also helpful for the monitoring of therapeutic response to antibacterial therapy.
Serum
SST (1)
2.0 mL
Plasma
Green - Lithium Heparin (2)
Allow specimen to clot for at least 15 minutes post-draw. Centrifuge and seperate serum from red cells within 2 hours of collection. Submit unopened tube refrigerated.
Must centrifuge within 2 hours of collection. The same specimen type (serum, plasma) should be used throughout the patient's clinical course.
An aid in monitoring antiresorptive and anabolic therapy in patients with osteoporosis. Useful in assessment of conditions associated with increased bone turnover such as Paget disease.
Useful for evaluation of ovulation in a menstrual cycle, evaluation of placental function in pregnancy, and workup of patients with adrenal or testicular tumors.
Useful for aiding in evaluation of pituitary tumors, amenorrhea, galactorrhea, infertility, and hypogonadism, and for monitoring of prolactin-producing tumors.
Useful for predicting recurrence after radical prostatectomy for clinically localized prostate cancer and following response to androgen ablation therapy, when used in conjunction with prostate-specific antigen.
Serum
SST (1)
None
None
Must obtain specimen before (or 48 hours post) rectal examination, biopsy, prostatectomy, or prostatic massage.
Useful as an initial test for evaluating patients suspected of having congenital protein C deficiency, including those with personal or family histories of thrombotic events, and for detecting and confirming congenital type I and type II protein C deficiencies. Also useful for detecting and confirming congenital homozygous protein C deficiency, and for identifying decreased functional protein C of acquired origin (eg, due to oral anticoagulant effect, vitamin K deficiency, liver disease, intravascular coagulation and fibrinolysis/disseminated intravascular coagulation).
Plasma
Lt. Blue (1)
None
None
Please note if PT is being treated with Coumadin. Spin TWICE and freeze plasma within 4 hours of collection.
Useful for differentiating congenital type I protein C deficiency from type II deficiency, for evaluating the significance of decreased functional protein C, especially when decreased protein C activity might be congenital rather than acquired (eg, due to oral anticoagulant effect, vitamin K deficiency, liver disease, or intravascular coagulation and fibrinolysis/disseminated intravascular coagulation). This test is not useful for predicting a thrombotic event.
Useful for evaluating patients with a history of venous thromboembolism, and as a second-order testing for diagnosis of congenital or acquired protein S deficiency. For example, as an adjunct to initial testing based on results of protein S antigen assay (free protein S antigen, with or without total protein S antigen assay).
Plasma
Lt. Blue (1)
None
None
PT cannot be receiving Coumadin. Spin TWICE and freeze plasma immediately.
Direct mutation analysis for the prothrombin (PT) 20210A allele should be reserved for patients with clinically suspected thrombophilia. There may be additional indications for direct PT 20210A mutation testing, such as in determining the duration of anticoagulation therapy of venous thromboembolism patients and screening for women contemplating hormone therapy.
Whole Blood
EDTA (1)
None
None
RT (5 Days)
6 Days
Hologic invader Assay
81240
Factor II 20210 mutation, Prothrombin 20210 mutation, Prothrombin Nucleotide, PTNT
Useful for assessing the risk of prostate cancer in patients with borderline or moderately increased total PSA (4.0-10.0 ng/mL) , and for determining which patients should have follow-up prostate biopsy.
Serum
SST
None
None
Avoid biotin (B7) for 12 HR prior to collection. Pour off serum within 3 hours of collection and freeze.
FREEZE (90 Days)
4 Days
Electrochemiluminescence Immunoassay (ECLIA)
84153, 84154
Free PSA, PSA Free/Total Ratio, PSA Total and Free, PSA Ratio
Ultra sensitive PSA, useful for close monitoring of patients with a history of prostate cancer, as an early indicator of recurrence, and for measuring response to treatment.
Serum
SST (1)
None
Red (1)
Collect specimen prior to or at least one week after biopsy, rectal exam, or ther manipulation of prostate. Pour off and freeze serum as soon as possible.
FREEZE (30 Days)
4 Days
Chemiluminescence
84153
Ultra Sensitive PSA, Prostate Specific Antigen Ultra Sensitive
Aides in the diagnosis of hypercalcemia, hyperparathyroidism, and hypoparathyroidism, and monitors end-stage renal failure for possible renal osteodystrophy.
Prenatal screening for open neural tube defect (alpha-fetoprotein only), trisomy 21 (alpha-fetoprotein, human chorionic gonadotropin, estriol, and inhibin A) and trisomy 18 (alpha-fetoprotein, human chorionic gonadotropin, and estriol).
Serum
SST (1)
None
None
Do not draw after amniocentesis. Centrifuge and pour off serum immediately. See web link for additional details.
Used to help diagnose and manage conditions affecting kidney function, and may be used as part of general health screening or to screen someone who is at risk of developing kidney disease.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
REFRIGERATE (7 Days)
Various (See individual test methodology)
80069
Kidney Function Panel, Kidney Function Test, RFP, KFT
Useful in the investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter syndrome).
Plasma
EDTA (1)
None
None
PT must discontinue spironolactone at least 4-6 weeks prior to testing. Draw in a chilled EDTA tube and place immediately on wet ice. Centrifuge chilled if possible for less than or equal to 5 minutes, then promptly transfer and freeze specimen.
FREEZE (14 Days)
6 Days
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Useful as an adjunct in the evaluation of patients with lupus erythematosus (LE). This test aids in the differential diagnosis of neuropsychiatric symptoms in patients with LE.
Useful for evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive. Not useful in patients without demonstrable antinuclear antibodies.
Useful for the determination of immune status of individuals to the measles virus, and for documentation of previous infection with measles virus in an individual without a previous record of immunization to measles virus.
The presence of IgG antibodies to the nucleocapsid protein of SARS-CoV-2 in serum may be indicative of recent infection and ma be useful in assessing community prevalence of immunity.
Serum
SST (1)
None
None
REFRIGERATE (7 Days)
48 Hours
Two-step Immunoassay using CMIA (Chemiluminescent Microparticle Immunoassay)
Useful for evaluating patients with signs and symptoms of scleroderma and other connective tissue diseases in whom the test for antinuclear antibodies is positive. Not useful in patients without demonstrable antinuclear antibodies.
Serum
SST (1)
None
None
REFRIGERATE (48 Hours)
4 Days
Enzyme Immunoassay
86235
Autoantibodies to Scl 70 Antigen, DNA Topoisomerase 1 Antibodies, Scl70, Topoisomerase 1 Antibodies, Scleroderma Antibodies
Useful to detect the presence of inflammation caused by one or more conditions such as infections, tumors, or autoimmune diseases. Used to help diagnose and monitor specific conditions such as temporal arteritis, systemic vasculitis, polymyalgia rheumatica, or rheumatoid arthritis.
Whole Blood
EDTA (1)
None
None
REFRIGERATE (24 Hours)
Mini Cube
85651
Sedimentation Rate, ESR, Erythrocytes Sedimentation Rate, Sed Rate
A prenatal screening for Down Syndrome, Neural Tube Defects (NTD), and Trisomy 18. Useful for identifying abnormal levels of alpha-fetoprotein in the second trimester. Includes: Alpha-Fetoprotein (AFP), Human Gonadotropin (hCG), Unconjugated Estriol (UE3), and Inhibin A. Requires result from Sequential Screen 1.
Serum
SST (1)
None
Red (1)
Centrifuge and separate from cells within 2 hours of collection. Samples should be collected between 15 weeks and 0 days and 22 weeks 6 days gestation. Completed Prenatal Screen Information Sheet must accompany sample.
A prenatal screening for Down syndrome and trisomy 18. Includes: Pregnancy Associated Plasma Protein-A (PAPP-A), Human Chorionic Gonadotropin (hCG), and Nuchal Translucency (NT). Risk assessment not reported until Sequntial Screen 2 is completed.
Serum
SST (1)
None
Red (1)
Centrifuge and separate from cells within 2 hours of collection. Samples should be collected between 10 weeks and 3 days (CRL 36mm) and 13 weeks 6 days gestation (CRL 79.9mm). Completed Prenatal Screen Information Sheet must accompany sample.
Used in the differential diagnosis of isolated symptoms suggestive of carcinoid syndrome, in particular flushing (5-HIAA or serum chromogranin A measurements are first-line tests). Also useful as a second-order test in the follow-up of patients with known or treated carcinoid umors in serum specimens.
Serum
SST (1), Red (1)
None
None
PT should avoid avocados, bananas, eggplant, pineapple, plums, tomatoes, and walnuts for a 48 hour period prior to draw. Spin and freeze within 2 hours.
FREEZE (42 Days)
8 Days
High Performance Liquid Chromatography, Fluorescence Detection
Useful as an adjunct in diagnosis of puberty disorders, androgen excess (polycystic ovarian syndrome and idiopathic hirsutism), anorexia nervosa, thyrotoxicosis, insulin resistance, and a woman's type 2 diabetes risk-assessment.
Serum
SST (1)
Plasma
Green (1)
REFRIGERATE (7 Days)
CMIA
84270
Sex Steroid Binding Protein (SBP), SHBG, TeBG, Testosterone-Estradiol Binding Globulin
A screening for the presence or absence of hemoglobin S. Heterozygous hemoglobin S is the most common form of hemoglobinopathy in the US. It detects only the presence of Hb S and cannot differentiate the sickle-cell trait from sickle-cell disease.
Useful when monitoring whole blood sirolimus concentration during therapy, particularly in individuals coadministered CYP3A4 substrates, inhibitors, or inducers. Also useful for adjusting dose to optimize immunosuppression while minimizing toxicity, and for evaluating patient compliance.
Useful for evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive, especially those with signs and symptoms consistent with Sjogren syndrome or lupus erythematosus. Not useful in patients without demonstrable antinuclear antibodies.
Useful for evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive. Not useful in patients without demonstrable antinuclear antibodies.
Serum
SST (1)
None
None
REFRIGERATE (48 Hours)
3 Days
Enzyme Immunoassay
86235
Anti-Smith (Sm) Antigen, Autoantibodies to Sm (Smith), Smith Antigen, SmRNP Autoantibodies, Smth
Useful when evaluating a patient for autoimmune hepatitis. Usually ordered when a person presents with symptoms such as fatigue and jaundice along with abnormal findings on routine liver tests such as aspartate aminotransferase (AST) and/or bilirubin. These autoantibody tests may be ordered along with other testing when a healthcare practitioner is investigating liver disease and wants to distinguish between different causes of liver injury, including viral infections, drugs, alcohol abuse, toxins, genetic conditions, metabolic conditions, and autoimmune disorders.
Useful for evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive, especially those with signs and symptoms consistent with Sjogren syndrome or lupus erythematosus. Not useful in patients without demonstrable antinuclear antibodies.
Useful for evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive, especially those with signs and symptoms consistent with Sjogren syndrome or lupus erythematosus. Not useful in patients without demonstrable antinuclear antibodies.
A test that detects and identifies bacteria that cause infections of the lower digestive tract. Distinguishes between the types of bacteria that cause disease (pathogenic) and the types that are normally found in the digestive tract (normal flora).
Useful for conditions associated with increased fecal leukocytes including antibiotic-associated colitis, ulcerative colitis, shigellosis, salmonellosis, Campylobacter, Yersinia, and amoebiasis.
Useful for qualitative detection of IgG and IgM antibodies directed against Treponema pallidum (TP) in human serum or plasma. It is intended to be used as an initial diagnostic testor or in conjunction with a nontreponemal laboratory test and clinical findings to aid in the diagnosis of syphilis infection.
Useful for monitoring treatment with synthetic hormones and treatment of hyperthyroidism. Total T4 levels offer a good index of thyroid function when the thyroid-binding globulin is normal and nonthyroidal illness is not present.
Useful for monitoring whole blood tacrolimus concentration during therapy, particularly in individuals coadministered CYP3A4 substrates, inhibitors, or inducers. Also useful for adjusting dose to optimize immunosuppression while minimizing toxicity, and for evaluating patient compliance.
Alternative, second-level test for suspected increases or decreases in physiologically active testosterone indications. Useful in the assessment of androgen status in cases with suspected or known sex hormone-binding globulin-binding abnormalities, the assessment of functional circulating testosterone in early pubertal boys and older men, the assessment of functional circulating testosterone in women with symptoms or signs of hyperandrogenism with normal total testosterone levels, and the monitoring of testosterone therapy or antiandrogen therapy in older men and in females.
Useful for evaluation of men for possible hypogonadism, precocious puberty, idiopathic hirsutism, and male-to-female transgender disorders. Also useful for the evaluation of women with hirsutism, virilization, oligoamenorrhea, and testosterone deficiency, and the evaluation of infants with ambiguous testosterone deficiency, ambiguous genitalia, or virilization. Useful in the diagnosis of androgen-secreting tumors.
Serum
Red (1)
None
None
REFRIGERATE (4 Days)
7 Days
Liquid Chromatography-Tandem Mass Spectromentry (LC-MS/MS)
Useful for evaluation of men for possible hypogonadism, precocious puberty, idiopathic hirsutism, and male-to-female transgender disorders. Also useful for the evaluation of women with hirsutism, virilization, oligoamenorrhea, and testosterone deficiency, and the evaluation of infants with ambiguous testosterone deficiency, ambiguous genitalia, or virilization. Useful in the diagnosis of androgen-secreting tumors.
The recommended second-level test for suspected increases or decreases in physiologically active testosterone. Useful in the assessment of androgen status in cases with suspected or known sex hormone-binding-globulin-binding abnormalities, the assessment of functional circulating testosterone in early pubertal boys and older men, the assessment of functional circulating testosterone in women with symptoms or signs of hyperandrogenism but normal total testosterone levels, and the monitoring of testosterone therapy or antiandrogen therapy in older men and in females.
Serum
Red (2)
None
None
REFRIGERATE (21 Days)
7 Days
Liquid Chromatography Tandem Mass Spectrometry, Calculation, Spectrophotometry, Immunochemiluminescent Assay
Alternative, second-level test for suspected increases or decreases in physiologically active testosterone. Used in the assessment of androgen status in cases with suspected SHBG-binding abnormalities, the assessment of functional circulating testosterone in early pubescent boys and older men, and in women with symptoms or signs of hyperandrogenism with normal testosterone levels. Also used for monitoring of testosterone therapy in older males and females.
Useful in the assessment of an antibody response to the tetanus toxoid vaccine, which should be performed at least 3 weeks after immunization. An aid to diagnose immunodeficiency.
Useful for the extensive and economical diagnosis and classification of hemoglobinopathies or thalassemia (including complex disorders), the evaluation of microcytosis, and the diagnosis of hereditary persistence of hemoglobin (HPFH).
Whole Blood & Serum
EDTA (3) & SST (1)
None
None
Must draw both serum and whole blood. Send whole blood specimens in original tubes, DO NOT ALIQUOT.
Useful for detection of individuals with low thiopurine methyltransferase (TPMT) activity who are at risk for excessive myelosuppression or severe hematopoietic toxicity when taking thiopurine drugs, and for the detection of individuals with hyperactive TPMT activity who have therapeutic resistance to thiopurine drugs and may develop hepatotoxicity if treated with these drugs.
Plasma
EDTA (2)
None
None
Abstain from the following for at least 48 HR prior to collection: naproxen (Aleve), ibuprofen (Advil, Motrin), ketoprofen (Orudis), furosemide (Lasix), sulfasalazine (Azulfidine), mesalamine (Asacol), olsalazine (Dipentum), mefenamic acid (Ponstel), trimethoprin (Proloprim), methotrexate, thiazide diuretics, and benzoic acid inhibitors.
REFRIGERATE (6 Days)
7 Days
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Useful in detecting or excluding the presence of heparin or heparin-like anticoagulants (which act by enhancing antithrombin's inhibition of thrombin and other procoagulant enzymes) when used in conjunction with reptilase time (RT) in evaluating unexplained prolonged clotting times. Also useful in identifying the cause of a prolonged prothrombin time, activated partial thromboplastin time, or dilute Russell viper venom time when used in conjunction with the RT and fibrinogen assay.
Plasma
Lt. Blue (1)
None
None
Fasting preferred (12 HR). Spin TWICE and freeze plasma within 4 hours of collection.
Useful for differentiating thyroid autoimmune disorders from nonautoimmune goiter or hypothyroidism, for aiding in treatment for patients with subclinical hypothyroidism, and for aiding in the diagnosis of Hashimoto disease, postpartum thyroiditis, neonatal hypothyroidism, and Graves disease.
Serum
SST (1)
Plasma
Green (1) Lithium Heparin
REFRIGERATE (72 Hours)
CMIA
86376, 86800
Thyroglobulin and Thyroid Peroxidase Antibodies, TPO and Thyroglobulin, Thyroperoxidase Ab and Thyroglobulin
Useful for aiding in the diagnosis of thyroid autoimmune disorders, for differentiating thyroid autoimmune disorders from nonautoimmune goiter or hypothyroidism, and for deciding whether to undergo treatment for subclinical hypothyroidism.
Useful as second-order testing for autoimmune thyroid disease (including: Differential diagnosis of etiology of thyrotoxicosis) in patients with ambiguous clinical signs or contraindicated (eg, pregnant or breast-feeding) or indeterminate thyroid radioisotope scans. Aids in the diagnosis of clinically suspected Graves disease (eg, extrathyroidal manifestations of Graves disease: endocrine exophthalmos, pretibial myxedema, thyroid acropachy) with normal thyroid function tests, and in determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past Graves disease. Useful in the differential diagnosis of gestational thyrotoxicosis versus first-trimester manifestation or recurrence of Graves disease, and for assessing the risk of Graves disease relapse after antithyroid drug treatment.
Determination of thyroxine-binding globulin levels is particularly useful for cases in which total thyroid hormone levels do not correlate with the thyrometabolic status, most commonly with pregnancy or the use of contraceptive steroids.
Useful for evaluating individuals with IgA deficiency, patients suspected of having celiac disease (including patients with compatible clinical symptoms), patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disorder, positivity for HLA DQ2 and/or DQ8). Useful as a screening test for dermatitis herpetiformis, in conjunction with the endomysial antibody test, and for monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease.
Serum
SST (1)
None
None
REFRIGERATE (48 Hours)
4 Days
Enzyme-Linked Immunoassay
83516
Celiac Disease, Coeliac Disease, tTG, Transglutaminase, Tissue Transglutaminase Ab IGG
Useful as an evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disorder, positivity for HLA DQ2 and/or DQ8). Useful as a screening test for dermatitis herpetiformis, in conjunction with the endomysial antibody test, and for monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease.
Serum
SST (1)
None
None
REFRIGERATE (7 Days)
4 Days
Enzyme-Linked Immunoassay
83516
Celiac Disease, Coeliac Disease, tTG, Transglutaminase, Tissue Transglutaminase Ab IGA
Useful for the determination of immune status of individuals to the rubella virus following vaccination or prior exposure, as an indication of past or recent infection with Toxoplasma gondii, cytomegalovirus, or herpes simplex virus (HSV), and to distinguishing between infection caused by HSV types 1 and 2, especially in patients with subclinical or unrecognized HSV infection.
Used for quantitative detection of specific IgM antibodies to TORCH. Positive result for TORCH IgM indicates possible acute infection with TORCH. Negative result indicates no serological evidence of infection with TORCH. False negative can be due to immunosuppression or due to low/undetectable level of IgM antibodies. A suspected diagnosis of acute TORCH infection should be confirmed by PCR analysis or repeat test after 10-14 days.
Aides in assessing liver function and evaluation of a wide range of disease affecting the production, uptake, storage, metabolism, or excretion of bilirubin. Aides in monitoring the efficacy of neonatal phototherapy.
Useful for the diagnosis and treatment of a variety of diseases involving the liver, kidney, or bone marrow, as well as other metabolic or nutritional disorders.
Useful as an aid to resolve discrepant results between screening treponemal (eg, enzyme immunoassay [EIA], multiplex flow immunoassay) and nontreponemal (eg, rapid plasma regain) assays.
Serum
SST (1)
Plasma
EDTA (1)
REFRIGERATE (5 Days)
5 Days
Particle Agglutination
86780
Treponema pallidum, RPR, Rapid Plasma Reagin, Syphilis, T. Pallidum
Testing for hyperthyroidism in patients with low thyroid-stimulating hormone values and normal thyroxine levels. Used to diagnose triiodothyronine toxosis.
Serum
SST (1)
Plasma
Green (1)
REFRIGERATE (6 Days)
CMIA
84480
T3, Total T3, T3 Suppression, Triiodothyronine, Thyroid Function
Used when assessing mast cell activation, which may occur as a result of anaphylaxis or allergen challenge, and for assessing patients with systemic mastocytosis or mast cell activation syndrome.
Useful as a recommended first-line test for detection of thyrotropin receptor (TSHR) antibodies, and used in the following situations: differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or contraindicated (eg, pregnant or breast-feeding) or nondiagnostic thyroid radioisotope scans, diagnosis of clinically suspected Graves disease (eg, extrathyroidal manifestation of Graves disease include endocrine exophthalmos, pretibial myxedema, thyroid acropachy) in patients with normal thyroid function tests, determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past active Graves disease, differential diagnosis of gestational thyrotoxicosis versus first trimester manifestation or recurrence of Graves disease, and assessing the risk of Graves disease relapse after antithyroid drug treatment.
Serum
SST (1)
None
None
Allow serum to clot at room temperature for 1 hour before spinning and pouring off.
Useful for the rapid, sensitive, and specific identification of Ureaplasma urealyticum and U parvum from genitourinary, reproductive, bone and joint, and lower respiratory sources.
Various
Varies (1)
None
None
Specimen source required.
REFRIGERATE (7 Days)
5 Days
Real-Time PCR using LightCycler and Fluorescent Resonance Energy Transfer (FRET)
Useful for the diagnosis and treatment of renal failure, monitoring patients receiving cytotoxic drugs, and for a variety of other disorders including gout, leukemia, psoriasis, starvation, and other wasting conditions.
Useful for the identification of abnormal physiologic states causing excess or suppressed excretion of calcium (such as hyperparathyroidism), vitamin D abnormality, diseases that destroy bone, prostate cancer, and drug treatment such as thiazide therapy.
Useful for assessing the cause of abnormal serum magnesium concentrations, determining whether nutritional magnesium loads are adequate, and/or calculating urinary calcium oxalate and calcium phosphate supersaturation to assess kidney stone risk.
Useful for screening children for catecholamine-secreting tumors with a 24-hour urine collection when requesting testing for only vanillylmandelic acid, for supporting a diagnosis of neuroblastoma, and for monitoring patients with a treated neuroblastoma.
Urine
24 Hour Urine Jug (1)
None
None
Discontinue L-dopa 24 HR before collection.
REFRIGERATE (28 Days)
5 Days
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Useful in the determination of immune status of individuals to the varicella-zoster virus (VZV) and documentation of previous infection with VZV in an individual without a previous record of immunization to VZV.
Measures the amount of vascular endothelial growth factor (VEGF) in your blood. VEGF is a substance that helps encourage the growth of new blood vessels.
Plasma
EDTA (1)
None
None
Immediately after collection, place tube on wet ice. Centrifuge for 10 minutes and freeze plasma within 30 minutes.
Useful for assessment of thiamine deficiency when measuring levels in patients with behavioral changes, eye signs, gait disturbances, delirium, and encephalopathy. Also useful for patients with questionable nutritional status, especially those who appear at risk and who also are being given insulin for hyperglycemia.
Whole Blood
EDTA (1)
None
None
Transfer 2.0 mL whole blood to amber vial and freeze. PROTECT FROM LIGHT. CRITICAL FROZEN. (Pour off using Amber Vial)
Useful for the diagnosis and evaluation of hypophosphatasia or determining the overall success of a vitamin B6 supplementation program.
Plasma
EDTA (1)
Serum
SST (1)
Fasting required (12 HR). PT must not consume alcohol for at least 24 HR prior to collection. Collect infant samples before next feeding. CRITICAL FROZEN. PROTECT FROM LIGHT. (Pour off using Amber Vial)
Useful for the diagnosis of Vitamin D deficiency, differential diagnosis of causes of rickets and osteomalacia, monitoring Vitamin D replacement therapy, and/or diagnosis of hypervitaminosis D.
Useful for evaluation of individuals with motor and sensory neuropathies, monitoring vitamin E status of premature infants requiring oxygenation, and for evaluation of persons with intestinal malabsorption of lipids.
Serum
SST (1)
None
None
Fasting required (12 HR). Collect infant samples before next feeding. PROTECT FROM LIGHT. (Pour off using Amber Vial)
REFRIGERATE (44 Days) PFL
6 Days
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Useful for the assessment of circulating vitamin K concentration.
Serum
SST (1)
Plasma
EDTA (1)
Fasting required (12 HR). PT must not consume alcohol for at least 24 HR prior to collection. CRITICAL FROZEN. PROTECT FROM LIGHT. (Pour off using Amber Vial)
Useful for the detection of deficiency or abnormality of von Willebrand factor (VWF) and related deficiency of factor VIII coagulant activity and Subtyping von Willebrand disease (VWD) as type 1 (most common), type 2 variants (less common), or type 3 (rare).
Plasma
Lt. Blue (2)
None
None
Draw into 2 Lt. BLUE tubes. CRITICAL FROZEN PLASMA.
Useful for the rapid testing for West Nile virus (WNV) RNA, and as an adjunctive test to serology for detection of early WNV infection. This assay should not be used for screening asymptomatic individuals and should only be used to test patients with signs and symptoms of West Nile virus (WNV) disease.
A method of preparing specimens for examination in which they are kept in their liquid state or suspended in a liquid, rather than being dried and then examined.
Useful for screening for the presence of IgM-class antibodies to Zika virus in symptomatic individuals, particularly symptomatic pregnant women, with either travel to a Zika virus endemic region or who have had sexual exposure to an individual with Zika virus.
Serum
SST (1)
None
Red (1)
Use for patients whose symptoms began, or whose documented exposure occurred, at least 14 days prior to testing.