Useful for diagnosing a congenital deficiency of coagulation factor II, for evaluating acquired deficiencies associated with liver disease or vitamin K deficiency, oral anticoagulant therapy, and antibody-induced deficiencies (eg, in association with lupus-like anticoagulant). Also useful for determining warfarin treatment stabilization in patients with nonspecific inhibitors (ie, lupus anticoagulant), determining degree of anticoagulation with warfarin to correlate with level of protein S, and the investigation of prolonged prothrombin time or activated partial thromboplastin time.
Useful for patients with clinically suspected thrombophilia and either activated protein C (APC)-resistance proven or suspected by a low or borderline APC-resistance ratio, or a family history of factor V Leiden.
RT (5 Days)
The genotype is determined by Invader-based detection for the normal and mutant (R506q) alleles in genomic DNA isolated from blood.
Activated protein C (APC) resistance mutation, APC resistance mutation, Factor V Leiden mutation
Useful for detecting increased or decreased fibrinogen (factor 1) concentration of acquired or congenital origin and monitoring severity and treatment of disseminated intravascular coagulation and fibrinolysis.
Lt. Blue (1)
Tube MUST be filled to line for testing. Freeze within 4 hours of draw.