Useful in the investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter syndrome).
PT must discontinue spironolactone at least 4-6 weeks prior to testing. Draw in a chilled EDTA tube and place immediately on wet ice. Centrifuge chilled if possible for less than or equal to 5 minutes, then promptly transfer and freeze specimen.
FREEZE (14 Days)
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Useful for evaluating patients with signs and symptoms of a connective tissue disease in whom the test for antinuclear antibodies is positive. Not useful in patients without demonstrable antinuclear antibodies.
Useful for the determination of immune status of individuals to the measles virus, and for documentation of previous infection with measles virus in an individual without a previous record of immunization to measles virus.